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Stabilization Mechanism for a Nonfibrillar Amyloid ß Oligomer Based on Formation of a Hydrophobic Core Determined by Dissipative Particle Dynamics.
Kawai, Ryoko; Chiba, Shuntaro; Okuwaki, Koji; Kanada, Ryo; Doi, Hideo; Ono, Masahiro; Mochizuki, Yuji; Okuno, Yasushi.
Afiliação
  • Kawai R; Graduate School of Medicine , Kyoto University , 53 Shogoin-Kawahara-cho , Sakyo-ku, Kyoto 606-8507 , Japan.
  • Chiba S; RIKEN Medical Sciences Innovation Hub Program , 1-7-22 Suehiro-cho , Tsurumi-ku, Yokohama 230-0045 , Japan.
  • Okuwaki K; Department of Chemistry and Research Center for Smart Molecules, Faculty of Science , Rikkyo University , 3-34-1 Nishi-ikebukuro , Toshima-ku, Tokyo 171-8501 , Japan.
  • Kanada R; RIKEN Compass to Healthy Life Research Complex Program , RIKEN, 6-7-1 minatojima Minami-machi , Chuo-ku, Kobe , Hyogo 650-0047 , Japan.
  • Doi H; National Institute of Advanced Industrial Science and Technology (AIST) , 1-1-1 Umezono , Tsukuba , Ibaraki 305-8568 , Japan.
  • Ono M; Graduate School of Pharmaceutical Sciences , Kyoto University , 46-29 Shimodachi-cho , Sakyo-ku, Kyoto 606-8501 , Japan.
  • Mochizuki Y; Department of Chemistry and Research Center for Smart Molecules, Faculty of Science , Rikkyo University , 3-34-1 Nishi-ikebukuro , Toshima-ku, Tokyo 171-8501 , Japan.
  • Okuno Y; Institute of Industrial Science , The University of Tokyo , 4-6-1 Komaba , Meguro-ku, Tokyo 153-8505 , Japan.
ACS Chem Neurosci ; 11(3): 385-394, 2020 02 05.
Article em En | MEDLINE | ID: mdl-31899612
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Peptídeos beta-Amiloides / Multimerização Proteica / Doença de Alzheimer Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Peptídeos beta-Amiloides / Multimerização Proteica / Doença de Alzheimer Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article