Harnessing the active site triad: merging hemilability, proton responsivity, and ligand-based redox-activity.
Dalton Trans
; 49(4): 960-965, 2020 Jan 28.
Article
em En
| MEDLINE
| ID: mdl-31907502
ABSTRACT
Metalloenzymes catalyze many important reactions by managing the proton and electron flux at the enzyme active site. The motifs utilized to facilitate these transformations include hemilabile, redox-active, and so called proton responsive sites. Given the importance of incorporating and understanding these motifs in the area of coordination chemistry and catalysis, we highlight recent milestones in the field. Work incorporating the triad of hemilability, redox-activity, and proton responsivity into single ligand scaffolds will be described.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Prótons
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Domínio Catalítico
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Galactose Oxidase
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article