A trans-dichloridoplatinum(II) complex of a monodentate nitrogen mustard: Synthesis, stability and cytotoxicity studies.

Karmakar, Subhendu; Chatterjee, Saptarshi; Purkait, Kallol; Mukherjee, Arindam

Karmakar, Subhendu; Chatterjee, Saptarshi; Purkait, Kallol; Mukherjee, Arindam.

Afiliação

Karmakar S; Department of Chemical Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur 741246, India; Institute for Drug Research, School of Pharmacy, The Hebrew University of Jerusalem, Jerusalem 9112102, Israel.
Chatterjee S; Department of Chemical Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur 741246, India.
Purkait K; Department of Chemical Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur 741246, India.
Mukherjee A; Department of Chemical Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur 741246, India. Electronic address: a.mukherjee@iiserkol.ac.in.

J Inorg Biochem ; 204: 110982, 2020 03.

Article em En | MEDLINE | ID: mdl-31911365

Assuntos

Antineoplásicos/farmacologia; Mecloretamina/análogos & derivados; Mecloretamina/farmacologia; Neoplasias/tratamento farmacológico; Compostos Organoplatínicos/química; Compostos Organoplatínicos/farmacologia; Antineoplásicos/química; Apoptose/efeitos dos fármacos; Ciclo Celular/efeitos dos fármacos; Proliferação de Células/efeitos dos fármacos; Cisplatino/farmacologia; Estabilidade de Medicamentos; Humanos; Mecloretamina/química; Estrutura Molecular; Neoplasias/patologia; Células Tumorais Cultivadas

Palavras-chave

9-Ethyl guanine; Anticancer; Apoptosis; Cytotoxicity; Nitrogen mustard; trans-Platinum(II) complex

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos Organoplatínicos / Mecloretamina / Neoplasias / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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