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TGF-ß orchestrates fibrogenic and developmental EMTs via the RAS effector RREB1.
Su, Jie; Morgani, Sophie M; David, Charles J; Wang, Qiong; Er, Ekrem Emrah; Huang, Yun-Han; Basnet, Harihar; Zou, Yilong; Shu, Weiping; Soni, Rajesh K; Hendrickson, Ronald C; Hadjantonakis, Anna-Katerina; Massagué, Joan.
Afiliação
  • Su J; Cancer Biology and Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Morgani SM; Developmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • David CJ; Wellcome Trust-Medical Research Council Centre for Stem Cell Research, University of Cambridge, Cambridge, UK.
  • Wang Q; Cancer Biology and Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Er EE; Tsinghua University School of Medicine, Department of Basic Sciences, Beijing, China.
  • Huang YH; Cancer Biology and Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Basnet H; Department of Histo-embryology, Genetics and Developmental Biology, Shanghai Key Laboratory of Reproductive Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Zou Y; Cancer Biology and Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Shu W; Cancer Biology and Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Soni RK; Gerstner Sloan Kettering Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Hendrickson RC; Cancer Biology and Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Hadjantonakis AK; Cancer Biology and Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Massagué J; Gerstner Sloan Kettering Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Nature ; 577(7791): 566-571, 2020 01.
Article em En | MEDLINE | ID: mdl-31915377

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Fibrose / Fator de Crescimento Transformador beta / Proteínas ras / Proteínas de Ligação a DNA / Transição Epitelial-Mesenquimal / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Fibrose / Fator de Crescimento Transformador beta / Proteínas ras / Proteínas de Ligação a DNA / Transição Epitelial-Mesenquimal / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article