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Oral butyrate does not affect innate immunity and islet autoimmunity in individuals with longstanding type 1 diabetes: a randomised controlled trial.
de Groot, Pieter F; Nikolic, Tatjana; Imangaliyev, Sultan; Bekkering, Siroon; Duinkerken, Gaby; Keij, Fleur M; Herrema, Hilde; Winkelmeijer, Maaike; Kroon, Jeffrey; Levin, Evgeni; Hutten, Barbara; Kemper, Elles M; Simsek, Suat; Levels, Johannes H M; van Hoorn, Flora A; Bindraban, Renuka; Berkvens, Alicia; Dallinga-Thie, Geesje M; Davids, Mark; Holleman, Frits; Hoekstra, Joost B L; Stroes, Erik S G; Netea, Mihai; van Raalte, Daniël H; Roep, Bart O; Nieuwdorp, Max.
Afiliação
  • de Groot PF; Department of Internal and Vascular Medicine, Academic Medical Center, Meibergdreef 9, Room D3-316, 1105 AZ, Amsterdam, the Netherlands. p.f.degroot@amsterdamumc.nl.
  • Nikolic T; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, the Netherlands.
  • Imangaliyev S; Department of Internal and Vascular Medicine, Academic Medical Center, Meibergdreef 9, Room D3-316, 1105 AZ, Amsterdam, the Netherlands.
  • Bekkering S; Department of Internal and Vascular Medicine, Academic Medical Center, Meibergdreef 9, Room D3-316, 1105 AZ, Amsterdam, the Netherlands.
  • Duinkerken G; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.
  • Keij FM; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, the Netherlands.
  • Herrema H; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, the Netherlands.
  • Winkelmeijer M; Department of Internal and Vascular Medicine, Academic Medical Center, Meibergdreef 9, Room D3-316, 1105 AZ, Amsterdam, the Netherlands.
  • Kroon J; Department of Internal and Vascular Medicine, Academic Medical Center, Meibergdreef 9, Room D3-316, 1105 AZ, Amsterdam, the Netherlands.
  • Levin E; Department of Internal and Vascular Medicine, Academic Medical Center, Meibergdreef 9, Room D3-316, 1105 AZ, Amsterdam, the Netherlands.
  • Hutten B; Department of Internal and Vascular Medicine, Academic Medical Center, Meibergdreef 9, Room D3-316, 1105 AZ, Amsterdam, the Netherlands.
  • Kemper EM; Department of Epidemiology, Amsterdam University Medical Centers, Academic Medical Centre, Amsterdam, the Netherlands.
  • Simsek S; Clinical Pharmacy, Amsterdam University Medical Centers, Academic Medical Centre, Amsterdam, the Netherlands.
  • Levels JHM; Department of Internal Medicine, Alkmaar Medical Center (MCA), Alkmaar, the Netherlands.
  • van Hoorn FA; Department of Internal and Vascular Medicine, Academic Medical Center, Meibergdreef 9, Room D3-316, 1105 AZ, Amsterdam, the Netherlands.
  • Bindraban R; Department of Internal and Vascular Medicine, Academic Medical Center, Meibergdreef 9, Room D3-316, 1105 AZ, Amsterdam, the Netherlands.
  • Berkvens A; Department of Internal and Vascular Medicine, Academic Medical Center, Meibergdreef 9, Room D3-316, 1105 AZ, Amsterdam, the Netherlands.
  • Dallinga-Thie GM; Department of Internal and Vascular Medicine, Academic Medical Center, Meibergdreef 9, Room D3-316, 1105 AZ, Amsterdam, the Netherlands.
  • Davids M; Department of Internal and Vascular Medicine, Academic Medical Center, Meibergdreef 9, Room D3-316, 1105 AZ, Amsterdam, the Netherlands.
  • Holleman F; Department of Internal and Vascular Medicine, Academic Medical Center, Meibergdreef 9, Room D3-316, 1105 AZ, Amsterdam, the Netherlands.
  • Hoekstra JBL; Department of Internal and Vascular Medicine, Academic Medical Center, Meibergdreef 9, Room D3-316, 1105 AZ, Amsterdam, the Netherlands.
  • Stroes ESG; Department of Internal and Vascular Medicine, Academic Medical Center, Meibergdreef 9, Room D3-316, 1105 AZ, Amsterdam, the Netherlands.
  • Netea M; Department of Internal and Vascular Medicine, Academic Medical Center, Meibergdreef 9, Room D3-316, 1105 AZ, Amsterdam, the Netherlands.
  • van Raalte DH; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.
  • Roep BO; Department for Genomics & Immunoregulation, Life and Medical Sciences Institute (LIMES), University of Bonn, Bonn, Germany.
  • Nieuwdorp M; Department of Internal and Vascular Medicine, Academic Medical Center, Meibergdreef 9, Room D3-316, 1105 AZ, Amsterdam, the Netherlands.
Diabetologia ; 63(3): 597-610, 2020 03.
Article em En | MEDLINE | ID: mdl-31915895

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autoimunidade / Ilhotas Pancreáticas / Ácido Butírico / Diabetes Mellitus Tipo 1 / Imunidade Inata Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Female / Humans / Male / Middle aged País como assunto: Europa Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autoimunidade / Ilhotas Pancreáticas / Ácido Butírico / Diabetes Mellitus Tipo 1 / Imunidade Inata Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Female / Humans / Male / Middle aged País como assunto: Europa Idioma: En Ano de publicação: 2020 Tipo de documento: Article