Meisoindigo Protects Against Focal Cerebral Ischemia-Reperfusion Injury by Inhibiting NLRP3 Inflammasome Activation and Regulating Microglia/Macrophage Polarization via TLR4/NF-&#954;B Signaling Pathway.

Ye, Yingze; Jin, Tong; Zhang, Xu; Zeng, Zhi; Ye, Baixin; Wang, Jinchen; Zhong, Yi; Xiong, Xiaoxing; Gu, Lijuan

Meisoindigo Protects Against Focal Cerebral Ischemia-Reperfusion Injury by Inhibiting NLRP3 Inflammasome Activation and Regulating Microglia/Macrophage Polarization via TLR4/NF-κB Signaling Pathway.

Ye, Yingze; Jin, Tong; Zhang, Xu; Zeng, Zhi; Ye, Baixin; Wang, Jinchen; Zhong, Yi; Xiong, Xiaoxing; Gu, Lijuan.

Afiliação

Ye Y; Central Laboratory, Renmin Hospital of Wuhan University, Wuhan, China.
Jin T; Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, China.
Zhang X; Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, China.
Zeng Z; Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, China.
Ye B; Department of Pathology, Renmin Hospital of Wuhan University, Wuhan, China.
Wang J; Department of Hematopathology, Renmin Hospital of Wuhan University, Wuhan, China.
Zhong Y; Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, China.
Xiong X; Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, China.
Gu L; Central Laboratory, Renmin Hospital of Wuhan University, Wuhan, China.

Front Cell Neurosci ; 13: 553, 2019.

Article em En | MEDLINE | ID: mdl-31920554

Palavras-chave

NLRP3 inflammasome; ischemic stroke; microglia/macrophage polarization; new therapies; toll-like receptor 4

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2019 Tipo de documento: Article