Essential functions of the CNOT7/8 catalytic subunits of the CCR4-NOT complex in mRNA regulation and cell viability.

Mostafa, Dina; Takahashi, Akinori; Yanagiya, Akiko; Yamaguchi, Tomokazu; Abe, Takaya; Kureha, Taku; Kuba, Keiji; Kanegae, Yumi; Furuta, Yasuhide; Yamamoto, Tadashi; Suzuki, Toru

Mostafa, Dina; Takahashi, Akinori; Yanagiya, Akiko; Yamaguchi, Tomokazu; Abe, Takaya; Kureha, Taku; Kuba, Keiji; Kanegae, Yumi; Furuta, Yasuhide; Yamamoto, Tadashi; Suzuki, Toru.

Afiliação

Mostafa D; Cell Signal Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa, Japan.
Takahashi A; Department of Biochemistry, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.
Yanagiya A; Cell Signal Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa, Japan.
Yamaguchi T; Cell Signal Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa, Japan.
Abe T; Department of Biochemistry and Metabolic Science, Graduate School of Medicine, Akita University, Akita, Japan.
Kureha T; Laboratory for Animal Resources and Genetic Engineering, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan.
Kuba K; Cell Signal Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa, Japan.
Kanegae Y; Department of Biochemistry and Metabolic Science, Graduate School of Medicine, Akita University, Akita, Japan.
Furuta Y; Research Center for Medical Science, Jikei University School of Medicine, Tokyo, Japan.
Yamamoto T; Laboratory for Animal Resources and Genetic Engineering, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan.
Suzuki T; Cell Signal Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa, Japan.

RNA Biol ; 17(3): 403-416, 2020 03.

Article em En | MEDLINE | ID: mdl-31924127

Assuntos

Exorribonucleases/metabolismo; RNA Mensageiro/metabolismo; Receptores CCR4/metabolismo; Proteínas Repressoras/metabolismo; Animais; Sobrevivência Celular/genética; Exorribonucleases/genética; Feminino; Fibroblastos/citologia; Fibroblastos/fisiologia; Masculino; Camundongos Knockout; Complexos Multiproteicos/genética; Complexos Multiproteicos/metabolismo; Poli A/genética; Poli A/metabolismo; Subunidades Proteicas; Estabilidade de RNA; RNA Mensageiro/genética; Receptores CCR4/genética; Proteínas Repressoras/genética

Palavras-chave

CNOT6/6L; CNOT7/8; The CCR4-NOT complex; cell viability; deadenylation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / RNA Mensageiro / Exorribonucleases / Receptores CCR4 Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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