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HSD3B1 genotype identifies glucocorticoid responsiveness in severe asthma.
Zein, Joe; Gaston, Benjamin; Bazeley, Peter; DeBoer, Mark D; Igo, Robert P; Bleecker, Eugene R; Meyers, Deborah; Comhair, Suzy; Marozkina, Nadzeya V; Cotton, Calvin; Patel, Mona; Alyamani, Mohammad; Xu, Weiling; Busse, William W; Calhoun, William J; Ortega, Victor; Hawkins, Gregory A; Castro, Mario; Chung, Kian Fan; Fahy, John V; Fitzpatrick, Anne M; Israel, Elliot; Jarjour, Nizar N; Levy, Bruce; Mauger, David T; Moore, Wendy C; Noel, Patricia; Peters, Stephen P; Teague, W Gerald; Wenzel, Sally E; Erzurum, Serpil C; Sharifi, Nima.
Afiliação
  • Zein J; Lerner Research Institute and the Respiratory Institute, Cleveland Clinic, Cleveland, OH 44195.
  • Gaston B; Herman Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN 46202.
  • Bazeley P; Lerner Research Institute and the Respiratory Institute, Cleveland Clinic, Cleveland, OH 44195.
  • DeBoer MD; Department of Pediatrics, University of Virginia, Charlottesville, VA 22904.
  • Igo RP; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH 44106.
  • Bleecker ER; Department of Medicine, University of Arizona Health Sciences, Tucson, AZ 85721.
  • Meyers D; Department of Medicine, University of Arizona Health Sciences, Tucson, AZ 85721.
  • Comhair S; Lerner Research Institute and the Respiratory Institute, Cleveland Clinic, Cleveland, OH 44195.
  • Marozkina NV; Department of Pediatrics, Rainbow Babies and Children's Hospital, and Case Western Reserve University, Cleveland, OH 44106.
  • Cotton C; Department of Pediatrics, Rainbow Babies and Children's Hospital, and Case Western Reserve University, Cleveland, OH 44106.
  • Patel M; Lerner Research Institute and the Respiratory Institute, Cleveland Clinic, Cleveland, OH 44195.
  • Alyamani M; Lerner Research Institute and the Respiratory Institute, Cleveland Clinic, Cleveland, OH 44195.
  • Xu W; Lerner Research Institute and the Respiratory Institute, Cleveland Clinic, Cleveland, OH 44195.
  • Busse WW; Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706.
  • Calhoun WJ; Department of Medicine, University of Texas Medical Branch, TX 77555.
  • Ortega V; Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27587.
  • Hawkins GA; Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27587.
  • Castro M; Department of Medicine, University of Kansas School of Medicine, Kansas City, KS 66160.
  • Chung KF; The National Heart & Lung Institute, Imperial College London, London SW7 2AZ, United Kingdom.
  • Fahy JV; Department of Pediatrics, San Francisco School of Medicine, University of California, San Francisco, CA 94143.
  • Fitzpatrick AM; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322.
  • Israel E; Department of Medicine, Harvard Medical School, Boston, MA 02115.
  • Jarjour NN; Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706.
  • Levy B; Department of Medicine, Harvard Medical School, Boston, MA 02115.
  • Mauger DT; Center for Biostatistics and Epidemiology, Pennsylvania State University School of Medicine, Hershey, PA 16802.
  • Moore WC; Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27587.
  • Noel P; Severe Asthma Research Program (SARP), National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20892.
  • Peters SP; Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27587.
  • Teague WG; Department of Pediatrics, University of Virginia, Charlottesville, VA 22904.
  • Wenzel SE; University of Pittsburgh Asthma Institute, University of Pittsburgh Medical Center-University of Pittsburgh School of Medicine, Pittsburgh, PA 15261.
  • Erzurum SC; Lerner Research Institute and the Respiratory Institute, Cleveland Clinic, Cleveland, OH 44195.
  • Sharifi N; Lerner Research Institute and the Respiratory Institute, Cleveland Clinic, Cleveland, OH 44195; sharifn@ccf.org.
Proc Natl Acad Sci U S A ; 117(4): 2187-2193, 2020 01 28.
Article em En | MEDLINE | ID: mdl-31932420
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Progesterona Redutase / Asma / Esteroide Isomerases / Glucocorticoides / Complexos Multienzimáticos Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Progesterona Redutase / Asma / Esteroide Isomerases / Glucocorticoides / Complexos Multienzimáticos Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article