Catalyzing the Hydrodefluorination of CF3-Substituted Alkenes by PhSiH3. H⢠Transfer from a Nickel Hydride.
J Am Chem Soc
; 142(10): 4793-4799, 2020 03 11.
Article
em En
| MEDLINE
| ID: mdl-31935083
ABSTRACT
The hydrodefluorination of CF3-substituted alkenes can be catalyzed by a nickel(II) hydride bearing a pincer ligand. The catalyst loading can be as low as 1 mol%. gem-Difluoroalkenes containing a number of functional groups can be formed in good to excellent yields by a radical mechanism initiated by H⢠transfer from the nickel hydride. The relative reactivity of various substrates supports the proposed mechanism, as does a TEMPO trapping experiment.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Silanos
/
Alcenos
/
Complexos de Coordenação
/
Hidrocarbonetos Fluorados
/
Níquel
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article