A comparison of three multimodality coronary 3D reconstruction methods.

ABSTRACT

The assessment of the severity of arterial stenoses is of utmost importance in clinical practice. Several image modalities invasive and non-invasive are nowadays available and can be utilized for the 3-dimensional (3D) reconstruction of the arterial geometry. Following our previous study, the present study was conducted to further strengthen the evaluation of three reconstruction methodologies, namely (i) the Quantitative Coronary Analysis (QCA), (ii) the Virtual Histology Intravascular Ultrasound VH-IVUS-Angiography hybrid method and (iii) the Coronary Computed Tomography Angiography (CCTA). Data from 13 patients were employed to perform a quantitative analysis using specific metrics, such as, the Mean Wall Shear Stress (mWSS), the Minimum Lumen diameter (MLD), the Reference Vessel Diameter (RVD), the Degree of stenosis (DS%), and the Lesion length (LL). A high correlation was observed for the mWSS metric between the three reconstruction methods, especially between the QCA and CCTA (r=0.974, P<; 0.001).