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Prime Editing: Precision Genome Editing by Reverse Transcription.
Yan, Jun; Cirincione, Ann; Adamson, Britt.
Afiliação
  • Yan J; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, USA; Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA.
  • Cirincione A; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, USA.
  • Adamson B; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, USA; Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA. Electronic address: badamson@princeton.edu.
Mol Cell ; 77(2): 210-212, 2020 01 16.
Article em En | MEDLINE | ID: mdl-31951546
Genome editing is a method for making targeted sequence changes to the genomes of living cells. Prime editing, recently reported by Anzalone et al. (2019), is a new technology that uses reverse transcription to "write" programmed sequence changes into genomic DNA and thus promises significant technical advances.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transcrição Reversa / Edição de Genes Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transcrição Reversa / Edição de Genes Idioma: En Ano de publicação: 2020 Tipo de documento: Article