Oxidative storm in a patient with acute rotenone-containing plant poisoning.
Am J Emerg Med
; 38(6): 1296.e1-1296.e3, 2020 06.
Article
em En
| MEDLINE
| ID: mdl-31956048
ABSTRACT
A 64-year-old woman presented with coma, seizure, and lactic acidosis after ingesting 80 yam bean seeds. This rotenone-containing seeds cause cellular asphyxia via blockage of the mitochondrial electron transport. Subsequent oxidative stress results in the formation of lipid peroxidation (LPO). Rotenone analysis via liquid chromatography mass spectrometry revealed the following 31,590 ng/mL in cooked yam bean seed and 100 ng/mL in the blood. We attempted to use N-acetylcysteine to alleviate oxidative stress and documented the continuous decline in the plasma concentration of LPO.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Rotenona
/
Pachyrhizus
Tipo de estudo:
Etiology_studies
Limite:
Female
/
Humans
/
Middle aged
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article