Amperometric Detection of dsDNA using an Acridine-Orange-Modified Glucose Oxidase.
Chempluschem
; 82(11): 1310, 2017 Nov.
Article
em En
| MEDLINE
| ID: mdl-31957188
ABSTRACT
Invited for this month's cover is the group of Prof.â
Dr. Wolfgang Schuhmann, Dr. Daliborka Jambrec and Dr. Adrian Ruff at Ruhr-Universität in Bochum, Germany. The cover picture shows a novel procedure for the preferential post-hybridization labeling of double-stranded DNA based on the intercalating compound acridine orange, which was covalently bound to glucose oxidase. Labeling with a highly active biocatalyst allows for a simple and sequence-independent amplification of the signal proportional to the amount of hybridized DNA that may be coupled with other amplification strategies. Read the full text of the article at 10.1002/cplu.201700279.
Texto completo:
1
Base de dados:
MEDLINE
Tipo de estudo:
Diagnostic_studies
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article