The Endocannabinoid System: A Target for Cancer Treatment.
Int J Mol Sci
; 21(3)2020 Jan 23.
Article
em En
| MEDLINE
| ID: mdl-31979368
ABSTRACT
In recent years, the endocannabinoid system has received great interest as a potential therapeutic target in numerous pathological conditions. Cannabinoids have shown an anticancer potential by modulating several pathways involved in cell growth, differentiation, migration, and angiogenesis. However, the therapeutic efficacy of cannabinoids is limited to the treatment of chemotherapy-induced symptoms or cancer pain, but their use as anticancer drugs in chemotherapeutic protocols requires further investigation. In this paper, we reviewed the role of cannabinoids in the modulation of signaling mechanisms implicated in tumor progression.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Canabinoides
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Movimento Celular
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Receptores de Canabinoides
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Endocanabinoides
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Neoplasias
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Neovascularização Patológica
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Antineoplásicos
Tipo de estudo:
Guideline
Limite:
Animals
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Female
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Humans
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Male
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article