HPV induction of APOBEC3 enzymes mediate overall survival and response to cisplatin in head and neck cancer.

Conner, Kayla L; Shaik, Asra N; Ekinci, Elmira; Kim, Seongho; Ruterbusch, Julie J; Cote, Michele L; Patrick, Steve M

Conner, Kayla L; Shaik, Asra N; Ekinci, Elmira; Kim, Seongho; Ruterbusch, Julie J; Cote, Michele L; Patrick, Steve M.

Afiliação

Conner KL; Department of Oncology, Wayne State University School of Medicine and Barbara Ann Karmanos Institute, Detroit, MI 48201, United States.
Shaik AN; Department of Oncology, Wayne State University School of Medicine and Barbara Ann Karmanos Institute, Detroit, MI 48201, United States.
Ekinci E; Department of Oncology, Wayne State University School of Medicine and Barbara Ann Karmanos Institute, Detroit, MI 48201, United States.
Kim S; Department of Oncology, Wayne State University School of Medicine and Barbara Ann Karmanos Institute, Detroit, MI 48201, United States.
Ruterbusch JJ; Department of Oncology, Wayne State University School of Medicine and Barbara Ann Karmanos Institute, Detroit, MI 48201, United States.
Cote ML; Department of Oncology, Wayne State University School of Medicine and Barbara Ann Karmanos Institute, Detroit, MI 48201, United States.
Patrick SM; Department of Oncology, Wayne State University School of Medicine and Barbara Ann Karmanos Institute, Detroit, MI 48201, United States. Electronic address: patricks@karmanos.org.

DNA Repair (Amst) ; 87: 102802, 2020 03.

Article em En | MEDLINE | ID: mdl-31981740

Assuntos

Antineoplásicos/uso terapêutico; Carcinoma de Células Escamosas/tratamento farmacológico; Carcinoma de Células Escamosas/virologia; Cisplatino/uso terapêutico; Citidina Desaminase/metabolismo; Neoplasias de Cabeça e Pescoço/tratamento farmacológico; Neoplasias de Cabeça e Pescoço/virologia; Papillomaviridae; Desaminases APOBEC; Antineoplásicos/farmacologia; Carboplatina/farmacologia; Linhagem Celular Tumoral; Cisplatino/farmacologia; Reparo de Erro de Pareamento de DNA; Reparo do DNA; Humanos; Oxaliplatina/farmacologia

Palavras-chave

APOBEC3; Cisplatin; HPV; Head and neck cancer; Survival

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Papillomaviridae / Carcinoma de Células Escamosas / Cisplatino / Citidina Desaminase / Neoplasias de Cabeça e Pescoço / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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