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Effect of long-acting ß-agonists/glucocorticoids on human airway epithelial cell cytokine, transcriptomic and oxidative stress responses to cannabis smoke.
Huff, Ryan D; Aguiar, Jennifer A; Tse, Wayne; Stämpfli, Martin R; McConkey, Brendan J; Doxey, Andrew C; Hirota, Jeremy A.
Afiliação
  • Huff RD; Division of Respiratory Medicine, Dept of Medicine, University of British Columbia, Vancouver, BC, Canada.
  • Aguiar JA; Joint first authors.
  • Tse W; Dept of Biology, University of Waterloo, Waterloo, ON, Canada.
  • Stämpfli MR; Joint first authors.
  • McConkey BJ; Division of Respiratory Medicine, Dept of Medicine, University of British Columbia, Vancouver, BC, Canada.
  • Doxey AC; Firestone Institute for Respiratory Health - Division of Respirology, Dept of Medicine, McMaster University, Hamilton, ON, Canada.
  • Hirota JA; McMaster Immunology Research Centre, Dept of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada.
ERJ Open Res ; 6(1)2020 Jan.
Article em En | MEDLINE | ID: mdl-31984210
ABSTRACT
LABA/GC intervention in airway epithelial cells exposed to cannabis smoke reduces levels of pro-inflammatory (CXCL8) and antiviral (CXCL10) mediators, while transcriptomic signatures of neutrophil-mediated immunity and oxidative stress remain elevated http//bit.ly/2qiSQhH.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article