Diallyl trisulfide, a H<sub>2</sub> S donor, inhibits cell growth of human papillary thyroid carcinoma KTC-1 cells through a positive feedback loop between H<sub>2</sub> S and cystathionine-gamma-lyase.

Xu, Shichen; Pan, Jie; Cheng, Xian; Zheng, Jiangxia; Wang, Xiaowen; Guan, Haixia; Yu, Huixin; Bao, Jiandong; Zhang, Li

Diallyl trisulfide, a H₂ S donor, inhibits cell growth of human papillary thyroid carcinoma KTC-1 cells through a positive feedback loop between H₂ S and cystathionine-gamma-lyase.

Xu, Shichen; Pan, Jie; Cheng, Xian; Zheng, Jiangxia; Wang, Xiaowen; Guan, Haixia; Yu, Huixin; Bao, Jiandong; Zhang, Li.

Afiliação

Xu S; NHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, China.
Pan J; NHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, China.
Cheng X; School of Food Science and Technology, Jiangnan University, Wuxi, China.
Zheng J; NHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, China.
Wang X; NHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, China.
Guan H; School of Food Science and Technology, Jiangnan University, Wuxi, China.
Yu H; NHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, China.
Bao J; School of Food Science and Technology, Jiangnan University, Wuxi, China.
Zhang L; Department of Endocrinology & Metabolism and Institute of Endocrinology, the First Hospital of China Medical University, Shenyang, China.

Phytother Res ; 34(5): 1154-1165, 2020 May.

Article em En | MEDLINE | ID: mdl-31984539

Assuntos

Compostos Alílicos/uso terapêutico; Cistationina gama-Liase/efeitos dos fármacos; Inibidores da Agregação Plaquetária/uso terapêutico; Sulfetos/uso terapêutico; Câncer Papilífero da Tireoide/tratamento farmacológico; Compostos Alílicos/farmacologia; Linhagem Celular Tumoral; Humanos; Inibidores da Agregação Plaquetária/farmacologia; Sulfetos/farmacologia

Palavras-chave

CTH; H2S; NF-κB; diallyl trisulfide; papillary thyroid carcinoma

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sulfetos / Inibidores da Agregação Plaquetária / Cistationina gama-Liase / Compostos Alílicos / Câncer Papilífero da Tireoide Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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