SCD1 activity promotes cell migration via a PLD-mTOR pathway in the MDA-MB-231 triple-negative breast cancer cell line.

Lingrand, Marine; Lalonde, Simon; Jutras-Carignan, Antoine; Bergeron, Karl-F; Rassart, Eric; Mounier, Catherine

Lingrand, Marine; Lalonde, Simon; Jutras-Carignan, Antoine; Bergeron, Karl-F; Rassart, Eric; Mounier, Catherine.

Afiliação

Lingrand M; Molecular Metabolism of Lipids Laboratory, Biological Sciences Department, University of Quebec in Montreal (UQAM), 141 President-Kennedy Avenue, Montreal, QC, H2X 1Y4, Canada.
Lalonde S; Molecular Metabolism of Lipids Laboratory, Biological Sciences Department, University of Quebec in Montreal (UQAM), 141 President-Kennedy Avenue, Montreal, QC, H2X 1Y4, Canada.
Jutras-Carignan A; Molecular Metabolism of Lipids Laboratory, Biological Sciences Department, University of Quebec in Montreal (UQAM), 141 President-Kennedy Avenue, Montreal, QC, H2X 1Y4, Canada.
Bergeron KF; Molecular Metabolism of Lipids Laboratory, Biological Sciences Department, University of Quebec in Montreal (UQAM), 141 President-Kennedy Avenue, Montreal, QC, H2X 1Y4, Canada.
Rassart E; Molecular Metabolism of Lipids Laboratory, Biological Sciences Department, University of Quebec in Montreal (UQAM), 141 President-Kennedy Avenue, Montreal, QC, H2X 1Y4, Canada.
Mounier C; Molecular Metabolism of Lipids Laboratory, Biological Sciences Department, University of Quebec in Montreal (UQAM), 141 President-Kennedy Avenue, Montreal, QC, H2X 1Y4, Canada. mounier.catherine@uqam.ca.

Breast Cancer ; 27(4): 594-606, 2020 Jul.

Article em En | MEDLINE | ID: mdl-31993937

Assuntos

Movimento Celular; Estearoil-CoA Dessaturase/metabolismo; Neoplasias de Mama Triplo Negativas/patologia; Linhagem Celular Tumoral; Conjuntos de Dados como Assunto; Intervalo Livre de Doença; Feminino; Humanos; Estimativa de Kaplan-Meier; Metástase Neoplásica; Ácido Oleico/metabolismo; Fosfolipase D/antagonistas & inibidores; Fosfolipase D/metabolismo; Proteínas Quinases S6 Ribossômicas 70-kDa/metabolismo; Transdução de Sinais/efeitos dos fármacos; Serina-Treonina Quinases TOR/antagonistas & inibidores; Serina-Treonina Quinases TOR/metabolismo; Neoplasias de Mama Triplo Negativas/mortalidade; Neoplasias de Mama Triplo Negativas/cirurgia

Palavras-chave

Mammalian target of rapamycin; Oleic acid; Phospholipase D; Stearoyl-coenzyme A desaturase-1; Triple-negative breast cancer

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estearoil-CoA Dessaturase / Movimento Celular / Neoplasias de Mama Triplo Negativas Limite: Female / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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