Exendin-4 regulates endoplasmic reticulum stress to protect endothelial progenitor cells from high-glucose damage.

Yang, Yong; Zhou, Yong; Wang, Yiyong; Wei, Xianglong; Wang, Tingzhong; Ma, Aiqun

Yang, Yong; Zhou, Yong; Wang, Yiyong; Wei, Xianglong; Wang, Tingzhong; Ma, Aiqun.

Afiliação

Yang Y; Department of Cardiovascular Internal Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China; Department of Cardiovascular Internal Medicine, Shenzhen Hospital of Southern Medical University, Shenzhen, Guangdong, China.
Zhou Y; Department of Oncology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong, China.
Wang Y; Department of Cardiovascular Medicine, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, China.
Wei X; Department of Cardiovascular Internal Medicine, Shenzhen Hospital of Southern Medical University, Shenzhen, Guangdong, China.
Wang T; Department of Cardiovascular Internal Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China; Key Laboratory of Molecular Cardiology, Xi'an Jiaotong University, Xi'an, Shaanxi, China; Key Laboratory of Environment and Genes Related to Diseases, Xi'an Jiaotong Uni
Ma A; Department of Cardiovascular Internal Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China; Key Laboratory of Molecular Cardiology, Xi'an Jiaotong University, Xi'an, Shaanxi, China; Key Laboratory of Environment and Genes Related to Diseases, Xi'an Jiaotong Uni

Mol Cell Probes ; 51: 101527, 2020 06.

Article em En | MEDLINE | ID: mdl-31996309

Assuntos

Apoptose/efeitos dos fármacos; Estresse do Retículo Endoplasmático/efeitos dos fármacos; Células Progenitoras Endoteliais/efeitos dos fármacos; Exenatida/farmacologia; Glucose/farmacologia; Animais; Peso Corporal/efeitos dos fármacos; Sobrevivência Celular/efeitos dos fármacos; Células Cultivadas; Diabetes Mellitus Experimental; Células Progenitoras Endoteliais/metabolismo; Sistema de Sinalização das MAP Quinases/efeitos dos fármacos; Masculino; Malondialdeído/sangue; Camundongos; Camundongos Endogâmicos C57BL; Espécies Reativas de Oxigênio/metabolismo; Superóxido Dismutase/sangue; Superóxido Dismutase/genética

Palavras-chave

Diabetes mellitus; Endoplasmic reticulum stress; Endothelial progenitor cells; Exendin-4

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Apoptose / Estresse do Retículo Endoplasmático / Células Progenitoras Endoteliais / Exenatida / Glucose Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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