Child Neurology: A young child with an undiagnosed case of dystonia responsive to l-dopa.
Neurology
; 94(7): 326-328, 2020 02 18.
Article
em En
| MEDLINE
| ID: mdl-32015175
ABSTRACT
Childhood-onset dystonias are a heterogeneously diverse group. There exists a specific set of dystonias that respond profoundly well to low doses of l-dopa (dopa-responsive dystonia [DRD]). Classical DRD is caused by deficiency of GTP cyclohydrolase 1 or tyrosine hydroxylase, but other conditions can cause dystonias that are partially responsive to dopamine. The idea of a diagnostic therapeutic trial with l-dopa for children who present with dystonia has been around for decades and is frequently advocated for; however, l-dopa trials are not without risk.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Distúrbios Distônicos
Tipo de estudo:
Diagnostic_studies
Limite:
Child, preschool
/
Humans
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Male
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article