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LPS-induced inflammation desensitizes hepatocytes to Fas-induced apoptosis through Stat3 activation-The effect can be reversed by ruxolitinib.
Markotic, Antonio; Flegar, Darja; Grcevic, Danka; Sucur, Alan; Lalic, Hrvoje; Turcic, Petra; Kovacic, Natasa; Lukac, Nina; Pravdic, Danijel; Vukojevic, Katarina; Cavar, Ivan; Kelava, Tomislav.
Afiliação
  • Markotic A; Laboratory for Molecular Immunology, Croatian Institute for Brain Research, School of Medicine, University of Zagreb, Zagreb, Croatia.
  • Flegar D; Center for Clinical Pharmacology, University Clinical Hospital Mostar, Mostar, Bosnia and Herzegovina.
  • Grcevic D; Laboratory for Molecular Immunology, Croatian Institute for Brain Research, School of Medicine, University of Zagreb, Zagreb, Croatia.
  • Sucur A; Department of Physiology, School of Medicine, University of Zagreb, Zagreb, Croatia.
  • Lalic H; Laboratory for Molecular Immunology, Croatian Institute for Brain Research, School of Medicine, University of Zagreb, Zagreb, Croatia.
  • Turcic P; Department of Physiology, School of Medicine, University of Zagreb, Zagreb, Croatia.
  • Kovacic N; Laboratory for Molecular Immunology, Croatian Institute for Brain Research, School of Medicine, University of Zagreb, Zagreb, Croatia.
  • Lukac N; Department of Physiology, School of Medicine, University of Zagreb, Zagreb, Croatia.
  • Pravdic D; Department of Physiology, School of Medicine, University of Zagreb, Zagreb, Croatia.
  • Vukojevic K; Department of Pharmacology, Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia.
  • Cavar I; Laboratory for Molecular Immunology, Croatian Institute for Brain Research, School of Medicine, University of Zagreb, Zagreb, Croatia.
  • Kelava T; Department of Anatomy, School of Medicine, University of Zagreb, Zagreb, Croatia.
J Cell Mol Med ; 24(5): 2981-2992, 2020 03.
Article em En | MEDLINE | ID: mdl-32022429
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirazóis / Fator de Necrose Tumoral alfa / Receptor fas / Fator de Transcrição STAT3 / Inflamação Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirazóis / Fator de Necrose Tumoral alfa / Receptor fas / Fator de Transcrição STAT3 / Inflamação Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article