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High-density neutrophils in MGUS and multiple myeloma are dysfunctional and immune-suppressive due to increased STAT3 downstream signaling.
Romano, A; Parrinello, N L; Simeon, V; Puglisi, F; La Cava, P; Bellofiore, C; Giallongo, C; Camiolo, G; D'Auria, F; Grieco, V; Larocca, F; Barbato, A; Cambria, D; La Spina, E; Tibullo, D; Palumbo, G A; Conticello, C; Musto, P; Di Raimondo, F.
Afiliação
  • Romano A; Department of Surgery and Medical Specialties, University of Catania, Catania, Italy.
  • Parrinello NL; Division of Hematology, Azienda Ospedaliera Policlinico e Vittorio Emanuele di Catania, Catania, Italy.
  • Simeon V; Division of Hematology, Azienda Ospedaliera Policlinico e Vittorio Emanuele di Catania, Catania, Italy.
  • Puglisi F; Dipartimento di Scienze Mediche, Chirurgiche e Tecnologie Avanzate "G.F. Ingrassia", University of Catania, Catania, Italy.
  • La Cava P; Laboratory of Pre-Clinical Research and Advanced Diagnostics, IRCCS-CROB, Rionero in Vulture (Pz), Potenza, Italy.
  • Bellofiore C; Department of Mental Health and Preventive Medicine, Medical Statistics Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.
  • Giallongo C; Division of Hematology, Azienda Ospedaliera Policlinico e Vittorio Emanuele di Catania, Catania, Italy.
  • Camiolo G; Division of Hematology, Azienda Ospedaliera Policlinico e Vittorio Emanuele di Catania, Catania, Italy.
  • D'Auria F; Department of Surgery and Medical Specialties, University of Catania, Catania, Italy.
  • Grieco V; Division of Hematology, Azienda Ospedaliera Policlinico e Vittorio Emanuele di Catania, Catania, Italy.
  • Larocca F; Division of Hematology, Azienda Ospedaliera Policlinico e Vittorio Emanuele di Catania, Catania, Italy.
  • Barbato A; Division of Hematology, Azienda Ospedaliera Policlinico e Vittorio Emanuele di Catania, Catania, Italy.
  • Cambria D; Laboratory of Pre-Clinical Research and Advanced Diagnostics, IRCCS-CROB, Rionero in Vulture (Pz), Potenza, Italy.
  • La Spina E; Laboratory of Pre-Clinical Research and Advanced Diagnostics, IRCCS-CROB, Rionero in Vulture (Pz), Potenza, Italy.
  • Tibullo D; Laboratory of Pre-Clinical Research and Advanced Diagnostics, IRCCS-CROB, Rionero in Vulture (Pz), Potenza, Italy.
  • Palumbo GA; Division of Hematology, Azienda Ospedaliera Policlinico e Vittorio Emanuele di Catania, Catania, Italy.
  • Conticello C; Division of Hematology, Azienda Ospedaliera Policlinico e Vittorio Emanuele di Catania, Catania, Italy.
  • Musto P; Biometec, Dipartimento di Scienze Biomediche e Biotecnologiche, University of Catania, Catania, Italy.
  • Di Raimondo F; Biometec, Dipartimento di Scienze Biomediche e Biotecnologiche, University of Catania, Catania, Italy.
Sci Rep ; 10(1): 1983, 2020 02 06.
Article em En | MEDLINE | ID: mdl-32029833
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Gamopatia Monoclonal de Significância Indeterminada / Transdução de Sinais / Suscetibilidade a Doenças / Fator de Transcrição STAT3 / Mieloma Múltiplo / Neutrófilos Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Gamopatia Monoclonal de Significância Indeterminada / Transdução de Sinais / Suscetibilidade a Doenças / Fator de Transcrição STAT3 / Mieloma Múltiplo / Neutrófilos Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article