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Validation of an Aptima-format Finnish new variant of Chlamydia trachomatis (FI-nvCT) surveillance assay, 2019.
Weinbaum, Barbara; Williams, Analee; Hadad, Ronza; Vinluan, Bryan; Puolakkainen, Mirja; Unemo, Magnus; Getman, Damon.
Afiliação
  • Weinbaum B; Research and Development, Hologic Inc., San Diego, United States.
  • Williams A; Research and Development, Hologic Inc., San Diego, United States.
  • Hadad R; World Health Organization Collaborating Centre for Gonorrhoea and Other Sexually Transmitted Infections (STIs), National Reference Laboratory for STIs, Department of Laboratory Medicine, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
  • Vinluan B; Research and Development, Hologic Inc., San Diego, United States.
  • Puolakkainen M; Department of Virology and Immunology, University of Helsinki and Helsinki University Hospital, HUSLAB, Helsinki, Finland.
  • Unemo M; World Health Organization Collaborating Centre for Gonorrhoea and Other Sexually Transmitted Infections (STIs), National Reference Laboratory for STIs, Department of Laboratory Medicine, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
  • Getman D; Research and Development, Hologic Inc., San Diego, United States.
Euro Surveill ; 25(5)2020 02.
Article em En | MEDLINE | ID: mdl-32046818
The Finnish new variant of Chlamydia trachomatis (FI-nvCT) is escaping diagnostics in Finland, Norway and Sweden. We have developed and validated an Aptima-format nucleic acid amplification test (NAAT) designed specifically to detect the FI-nvCT. This NAAT has high sensitivity (100%) and specificity (100%) for the FI-nvCT strain, enabling further investigation of the geographic distribution, prevalence and transmission of this diagnostic-escape mutant in screening populations in Europe.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Variação Genética / Infecções por Chlamydia / Chlamydia trachomatis / Análise de Sequência de RNA / Técnicas de Amplificação de Ácido Nucleico Tipo de estudo: Diagnostic_studies / Risk_factors_studies / Screening_studies Limite: Humans País como assunto: Europa Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Variação Genética / Infecções por Chlamydia / Chlamydia trachomatis / Análise de Sequência de RNA / Técnicas de Amplificação de Ácido Nucleico Tipo de estudo: Diagnostic_studies / Risk_factors_studies / Screening_studies Limite: Humans País como assunto: Europa Idioma: En Ano de publicação: 2020 Tipo de documento: Article