Analysis of the transgene insertion pattern in a transgenic mouse strain using long-read sequencing.

Suzuki, Osamu; Koura, Minako; Uchio-Yamada, Kozue; Sasaki, Mitsuho

Suzuki, Osamu; Koura, Minako; Uchio-Yamada, Kozue; Sasaki, Mitsuho.

Afiliação

Suzuki O; Laboratory of Animal Models for Human Diseases, National Institutes of Biomedical Innovation, Health and Nutrition,7-6-8 Saito-Asagi, Ibaraki, Ibaraki, Osaka 568-0085, Japan.
Koura M; Laboratory of Animal Models for Human Diseases, National Institutes of Biomedical Innovation, Health and Nutrition,7-6-8 Saito-Asagi, Ibaraki, Ibaraki, Osaka 568-0085, Japan.
Uchio-Yamada K; Laboratory of Animal Models for Human Diseases, National Institutes of Biomedical Innovation, Health and Nutrition,7-6-8 Saito-Asagi, Ibaraki, Ibaraki, Osaka 568-0085, Japan.
Sasaki M; Laboratory of Animal Models for Human Diseases, National Institutes of Biomedical Innovation, Health and Nutrition,7-6-8 Saito-Asagi, Ibaraki, Ibaraki, Osaka 568-0085, Japan.

Exp Anim ; 69(3): 279-286, 2020 Aug 05.

Article em En | MEDLINE | ID: mdl-32051389

Assuntos

Mutagênese Insercional; Análise de Sequência de DNA/métodos; Transgenes/genética; Animais; Genoma/genética; Camundongos Endogâmicos C57BL; Camundongos Transgênicos; Mutação; Sarcoglicanas/genética

Palavras-chave

long-read sequencer; mice; nanopore; transgene insertion pattern

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Mutagênese Insercional / Análise de Sequência de DNA / Transgenes Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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