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A novel BCMA PBD-ADC with ATM/ATR/WEE1 inhibitors or bortezomib induce synergistic lethality in multiple myeloma.
Xing, Lijie; Lin, Liang; Yu, Tengteng; Li, Yuyin; Cho, Shih-Feng; Liu, Jiye; Wen, Kenneth; Hsieh, Phillip A; Kinneer, Krista; Munshi, Nikhil; Anderson, Kenneth C; Tai, Yu-Tzu.
Afiliação
  • Xing L; Jerome Lipper Multiple Myeloma Center, LeBow Institute for Myeloma Therapeutics, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Lin L; Department of Hematology, Shandong Provincial Hospital affiliated to Shandong University, Jinan, 250021, Shandong, PR China.
  • Yu T; Jerome Lipper Multiple Myeloma Center, LeBow Institute for Myeloma Therapeutics, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Li Y; Jerome Lipper Multiple Myeloma Center, LeBow Institute for Myeloma Therapeutics, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Cho SF; Jerome Lipper Multiple Myeloma Center, LeBow Institute for Myeloma Therapeutics, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Liu J; School of Biotechnology, Tianjin University of Science and Technology, Key Lab of Industrial Fermentation Microbiology of the Ministry of Education, State Key Laboratory of Food Nutrition and Safety, Tianjin, 300457, PR China.
  • Wen K; Jerome Lipper Multiple Myeloma Center, LeBow Institute for Myeloma Therapeutics, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Hsieh PA; Division of Hematology & Oncology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
  • Kinneer K; Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
  • Munshi N; Jerome Lipper Multiple Myeloma Center, LeBow Institute for Myeloma Therapeutics, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Anderson KC; Jerome Lipper Multiple Myeloma Center, LeBow Institute for Myeloma Therapeutics, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Tai YT; Jerome Lipper Multiple Myeloma Center, LeBow Institute for Myeloma Therapeutics, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
Leukemia ; 34(8): 2150-2162, 2020 08.
Article em En | MEDLINE | ID: mdl-32060401
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Tirosina Quinases / Imunoconjugados / Proteínas de Ciclo Celular / Antígeno de Maturação de Linfócitos B / Proteínas Mutadas de Ataxia Telangiectasia / Bortezomib / Mieloma Múltiplo Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Tirosina Quinases / Imunoconjugados / Proteínas de Ciclo Celular / Antígeno de Maturação de Linfócitos B / Proteínas Mutadas de Ataxia Telangiectasia / Bortezomib / Mieloma Múltiplo Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article