The emergence of dyslexia in the developing brain.
Neuroimage
; 211: 116633, 2020 05 01.
Article
em En
| MEDLINE
| ID: mdl-32061802
ABSTRACT
Developmental dyslexia, a severe deficit in literacy learning, is a neurodevelopmental learning disorder. Yet, it is not clear whether existing neurobiological accounts of dyslexia capture potential predispositions of the deficit or consequences of reduced reading experience. Here, we longitudinally followed 32 children from preliterate to school age using functional and structural magnetic resonance imaging techniques. Based on standardised and age-normed reading and spelling tests administered at school age, children were classified as 16 dyslexic participants and 16 controls. This longitudinal design allowed us to disentangle possible neurobiological predispositions for developing dyslexia from effects of individual differences in literacy experience. In our sample, the disorder can be predicted already before literacy learning from auditory cortex gyrification and aberrant downstream connectivity within the speech processing system. These results provide evidence for the notion that dyslexia may originate from an atypical maturation of the speech network that precedes literacy instruction.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Córtex Auditivo
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Percepção da Fala
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Imageamento por Ressonância Magnética
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Desenvolvimento Infantil
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Dislexia
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Conectoma
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Idioma
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Rede Nervosa
Tipo de estudo:
Observational_studies
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Risk_factors_studies
Limite:
Child
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Child, preschool
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Female
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Humans
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Male
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article