Small fish, big prospects: using zebrafish to unravel the mechanisms of hereditary hearing loss.

Vona, Barbara; Doll, Julia; Hofrichter, Michaela A H; Haaf, Thomas; Varshney, Gaurav K

Vona, Barbara; Doll, Julia; Hofrichter, Michaela A H; Haaf, Thomas; Varshney, Gaurav K.

Afiliação

Vona B; Department of Otolaryngology--Head & Neck Surgery, Tübingen Hearing Research Centre, Eberhard Karls University Tübingen, Tübingen, Germany. Electronic address: barbara.vona@uni-tuebingen.de.
Doll J; Institute of Human Genetics, Julius Maximilians University, Würzburg, Germany.
Hofrichter MAH; Institute of Human Genetics, Julius Maximilians University, Würzburg, Germany.
Haaf T; Institute of Human Genetics, Julius Maximilians University, Würzburg, Germany.
Varshney GK; Genes & Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, United States. Electronic address: Gaurav-Varshney@omrf.org.

Hear Res ; 397: 107906, 2020 11.

Article em En | MEDLINE | ID: mdl-32063424

Assuntos

Perda Auditiva; Animais; Sistemas CRISPR-Cas; Edição de Genes; Audição/genética; Perda Auditiva/genética; Humanos; Peixe-Zebra/genética

Palavras-chave

Base editing; CRISPR/Cas9; Genetic variants; Genetics of hearing loss; Hereditary hearing loss; Model organism; Zebrafish

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Perda Auditiva Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Perda Auditiva Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article