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Superiority of temozolomide over radiotherapy for elderly patients with RTK II methylation class, MGMT promoter methylated malignant astrocytoma.
Wick, Antje; Kessler, Tobias; Platten, Michael; Meisner, Christoph; Bamberg, Michael; Herrlinger, Ulrich; Felsberg, Jörg; Weyerbrock, Astrid; Papsdorf, Kirsten; Steinbach, Joachim P; Sabel, Michael; Vesper, Jan; Debus, Jürgen; Meixensberger, Jürgen; Ketter, Ralf; Hertler, Caroline; Mayer-Steinacker, Regine; Weisang, Sarah; Bölting, Hanna; Reuss, David; Reifenberger, Guido; Sahm, Felix; von Deimling, Andreas; Weller, Michael; Wick, Wolfgang.
Afiliação
  • Wick A; Department of Neurology and Neurooncology Program, National Center for Tumor Diseases, Heidelberg University Hospital, Heidelberg, Germany.
  • Kessler T; Department of Neurology and Neurooncology Program, National Center for Tumor Diseases, Heidelberg University Hospital, Heidelberg, Germany.
  • Platten M; Clinical Cooperation Unit Neurooncology, German Cancer Consortium, German Cancer Research Center, Heidelberg, Germany.
  • Meisner C; Department of Neurology and Neurooncology Program, National Center for Tumor Diseases, Heidelberg University Hospital, Heidelberg, Germany.
  • Bamberg M; Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, German Cancer Consortium, German Cancer Research Center, Heidelberg, Germany.
  • Herrlinger U; Department of Neurology, University Medical Center Mannheim, Heidelberg University, Mannheim, Germany.
  • Felsberg J; General Neurology, Tübingen, Germany.
  • Weyerbrock A; Institute for Clinical Epidemiology and Applied Biometry, Tübingen, Germany.
  • Papsdorf K; Radiation Oncology, and German Cancer Consortium, partner site Tübingen, University of Tübingen, Tübingen, Germany.
  • Steinbach JP; Department of Neurology and Neurooncology, University of Bonn, Bonn, Germany.
  • Sabel M; Institute of Neuropathology, Heinrich Heine University, German Cancer Consortium, partner site Essen/Düsseldorf, Düsseldorf, Germany.
  • Vesper J; Neurosurgery Clinic, University Clinic Freiburg, and German Cancer Consortium, partner site Freiburg, Freiburg, Germany.
  • Debus J; Kantonsspital St Gallen, Neurosurgery Clinic, St-Gallen, Switzerland.
  • Meixensberger J; Departments of Radiation Oncology, Leipzig, Germany.
  • Ketter R; Dr Senckenbergisches Institute for Neurooncology, and German Cancer Consortium, partner site Frankfurt, University of Frankfurt, Frankfurt, Germany.
  • Hertler C; Department of Neurosurgery, Heinrich Heine University and German Cancer Consortium, partner site Essen/Düsseldorf, Düsseldorf, Germany.
  • Mayer-Steinacker R; Department of Neurosurgery, Heinrich Heine University and German Cancer Consortium, partner site Essen/Düsseldorf, Düsseldorf, Germany.
  • Weisang S; Radiation Oncology, National Center for Tumor Diseases, Heidelberg University Hospital, Heidelberg, Germany.
  • Bölting H; Neurosurgery, University Hospital Leipzig, Leipzig, Germany.
  • Reuss D; Department of Neurosurgery, University of Homburg, Homburg/Saar, Germany.
  • Reifenberger G; Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland.
  • Sahm F; Department of Internal Medicine III, University of Ulm, Ulm, Germany.
  • von Deimling A; Department of Neurology and Neurooncology Program, National Center for Tumor Diseases, Heidelberg University Hospital, Heidelberg, Germany.
  • Weller M; Department of Neurology and Neurooncology Program, National Center for Tumor Diseases, Heidelberg University Hospital, Heidelberg, Germany.
  • Wick W; Germany Clinical Cooperation Unit Neuropathology, German Cancer Research Center, Heidelberg, Germany.
Neuro Oncol ; 22(8): 1162-1172, 2020 08 17.
Article em En | MEDLINE | ID: mdl-32064499

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Astrocitoma / Neoplasias Encefálicas / Metilases de Modificação do DNA / Metilação de DNA / Proteínas Supressoras de Tumor / Enzimas Reparadoras do DNA / Temozolomida Tipo de estudo: Prognostic_studies Limite: Aged / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Astrocitoma / Neoplasias Encefálicas / Metilases de Modificação do DNA / Metilação de DNA / Proteínas Supressoras de Tumor / Enzimas Reparadoras do DNA / Temozolomida Tipo de estudo: Prognostic_studies Limite: Aged / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article