Influenza Classification Suite: An automated Galaxy workflow for rapid influenza sequence analysis.
Influenza Other Respir Viruses
; 14(3): 358-362, 2020 05.
Article
em En
| MEDLINE
| ID: mdl-32064792
ABSTRACT
Influenza viruses continually evolve to evade population immunity, and the different lineages are assigned into clades based on shared mutations. We have developed a publicly available computational workflow, the Influenza Classification Suite, for rapid clade mapping of sequenced influenza viruses. This suite provides a user-friendly workflow implemented in Galaxy to automate clade calling and antigenic site extraction. Workflow input includes clade definition and amino acid index array files, which can be customized to identify any clades of interest. The Influenza Classification Suite provides rapid, high-resolution understanding of circulating influenza strain evolution to inform influenza vaccine effectiveness and the need for potential vaccine reformulation.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Orthomyxoviridae
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Classificação
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Influenza Humana
Tipo de estudo:
Evaluation_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article