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Optically Pure Metallohelices That Accumulate in Cell Nuclei, Condense/Aggregate DNA, and Inhibit Activities of DNA Processing Enzymes.
Hrabina, Ondrej; Malina, Jaroslav; Kostrhunova, Hana; Novohradsky, Vojtech; Pracharova, Jitka; Rogers, Nicola; Simpson, Daniel H; Scott, Peter; Brabec, Viktor.
Afiliação
  • Hrabina O; Czech Academy of Sciences, Institute of Biophysics, Kralovopolska 135, CZ-61265 Brno, Czech Republic.
  • Malina J; Department of Biophysics, Centre of the Region Hana for Biotechnological and Agricultural Research, Palacky University, Slechtitelu 27, 783 71 Olomouc, Czech Republic.
  • Kostrhunova H; Czech Academy of Sciences, Institute of Biophysics, Kralovopolska 135, CZ-61265 Brno, Czech Republic.
  • Novohradsky V; Czech Academy of Sciences, Institute of Biophysics, Kralovopolska 135, CZ-61265 Brno, Czech Republic.
  • Pracharova J; Czech Academy of Sciences, Institute of Biophysics, Kralovopolska 135, CZ-61265 Brno, Czech Republic.
  • Rogers N; Czech Academy of Sciences, Institute of Biophysics, Kralovopolska 135, CZ-61265 Brno, Czech Republic.
  • Simpson DH; Department of Biophysics, Centre of the Region Hana for Biotechnological and Agricultural Research, Palacky University, Slechtitelu 27, 783 71 Olomouc, Czech Republic.
  • Scott P; Department of Chemistry, University of Warwick, Gibbet Hill Road, Coventry, CV4 7AL, United Kingdom.
  • Brabec V; Department of Chemistry, University of Warwick, Gibbet Hill Road, Coventry, CV4 7AL, United Kingdom.
Inorg Chem ; 59(5): 3304-3311, 2020 Mar 02.
Article em En | MEDLINE | ID: mdl-32064865
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA / Compostos Ferrosos / Núcleo Celular / DNA Topoisomerases Tipo I / Inibidores da Topoisomerase I Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA / Compostos Ferrosos / Núcleo Celular / DNA Topoisomerases Tipo I / Inibidores da Topoisomerase I Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article