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Programmable base editing of mutated TERT promoter inhibits brain tumour growth.
Li, Xinjian; Qian, Xu; Wang, Bin; Xia, Yan; Zheng, Yanhua; Du, Linyong; Xu, Daqian; Xing, Dongming; DePinho, Ronald A; Lu, Zhimin.
Afiliação
  • Li X; CAS Key Laboratory of Infection and Immunity, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China. lixinjian@ibp.ac.cn.
  • Qian X; University of Chinese Academy of Sciences, Beijing, China. lixinjian@ibp.ac.cn.
  • Wang B; Department of Nutrition and Food Hygiene, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.
  • Xia Y; Institute for Brain Tumors, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Jiangsu Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, China.
  • Zheng Y; CAS Key Laboratory of Infection and Immunity, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
  • Du L; University of Chinese Academy of Sciences, Beijing, China.
  • Xu D; Brain Tumor Center, Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Xing D; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • DePinho RA; Brain Tumor Center, Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Lu Z; School of Laboratory Medicine and Life Science, Wenzhou Medical University, Wenzhou, China.
Nat Cell Biol ; 22(3): 282-288, 2020 03.
Article em En | MEDLINE | ID: mdl-32066906
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Glioblastoma / Telomerase / Sistemas CRISPR-Cas / Edição de Genes Limite: Animals / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Glioblastoma / Telomerase / Sistemas CRISPR-Cas / Edição de Genes Limite: Animals / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article