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Widespread loss of the silencing epigenetic mark H3K9me3 in astrocytes and neurons along with hippocampal-dependent cognitive impairment in C9orf72 BAC transgenic mice.
Jury, Nur; Abarzua, Sebastian; Diaz, Ivan; Guerra, Miguel V; Ampuero, Estibaliz; Cubillos, Paula; Martinez, Pablo; Herrera-Soto, Andrea; Arredondo, Cristian; Rojas, Fabiola; Manterola, Marcia; Rojas, Adriana; Montecino, Martín; Varela-Nallar, Lorena; van Zundert, Brigitte.
Afiliação
  • Jury N; Institute of Biomedical Sciences (ICB), Faculty of Medicine & Faculty of Life Sciences, Universidad Andres Bello, Santiago, Chile.
  • Abarzua S; CARE Biomedical Research Center, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile.
  • Diaz I; Institute of Biomedical Sciences (ICB), Faculty of Medicine & Faculty of Life Sciences, Universidad Andres Bello, Santiago, Chile.
  • Guerra MV; CARE Biomedical Research Center, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile.
  • Ampuero E; FONDAP Center for Genome Regulation, Santiago, Chile.
  • Cubillos P; Institute of Biomedical Sciences (ICB), Faculty of Medicine & Faculty of Life Sciences, Universidad Andres Bello, Santiago, Chile.
  • Martinez P; CARE Biomedical Research Center, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile.
  • Herrera-Soto A; Institute of Biomedical Sciences (ICB), Faculty of Medicine & Faculty of Life Sciences, Universidad Andres Bello, Santiago, Chile.
  • Arredondo C; Institute of Biomedical Sciences (ICB), Faculty of Medicine & Faculty of Life Sciences, Universidad Andres Bello, Santiago, Chile.
  • Rojas F; CARE Biomedical Research Center, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile.
  • Manterola M; Current address: Faculty of Health Sciences, Universidad Autónoma de Chile, Santiago, Chile.
  • Rojas A; Institute of Biomedical Sciences (ICB), Faculty of Medicine & Faculty of Life Sciences, Universidad Andres Bello, Santiago, Chile.
  • Montecino M; CARE Biomedical Research Center, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile.
  • Varela-Nallar L; Institute of Biomedical Sciences (ICB), Faculty of Medicine & Faculty of Life Sciences, Universidad Andres Bello, Santiago, Chile.
  • van Zundert B; CARE Biomedical Research Center, Faculty of Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile.
Clin Epigenetics ; 12(1): 32, 2020 02 18.
Article em En | MEDLINE | ID: mdl-32070418
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Histonas / Epigênese Genética / Disfunção Cognitiva / Proteína C9orf72 Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Histonas / Epigênese Genética / Disfunção Cognitiva / Proteína C9orf72 Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article