Vorinostat and Belinostat, hydroxamate-based anti-cancer agents, are nitric oxide donors.

Kenny, Reece G; Ude, Ziga; Docherty, James R; Marmion, Celine J

Kenny, Reece G; Ude, Ziga; Docherty, James R; Marmion, Celine J.

Afiliação

Kenny RG; Centre for Synthesis and Chemical Biology, Department of Chemistry, Royal College of Surgeons in Ireland (RCSI), 123 St. Stephen's Green, Dublin 2, Ireland.
Ude Z; Centre for Synthesis and Chemical Biology, Department of Chemistry, Royal College of Surgeons in Ireland (RCSI), 123 St. Stephen's Green, Dublin 2, Ireland.
Docherty JR; Department of Physiology, Royal College of Surgeons in Ireland (RCSI), 123 St. Stephen's Green, Dublin 2, Ireland.
Marmion CJ; Centre for Synthesis and Chemical Biology, Department of Chemistry, Royal College of Surgeons in Ireland (RCSI), 123 St. Stephen's Green, Dublin 2, Ireland. Electronic address: cmarmion@rcsi.ie.

J Inorg Biochem ; 206: 110981, 2020 05.

Article em En | MEDLINE | ID: mdl-32088592

Assuntos

Aorta/efeitos dos fármacos; Guanilato Ciclase/metabolismo; Ácidos Hidroxâmicos/farmacologia; Doadores de Óxido Nítrico/farmacologia; Sulfonamidas/farmacologia; Vasodilatação/efeitos dos fármacos; Vasodilatadores/farmacologia; Vorinostat/farmacologia; Animais; Antineoplásicos; Aorta/metabolismo; Ácidos Hidroxâmicos/química; Ratos; Rutênio/química

Palavras-chave

Belinostat; Histone deacetylase inhibitors; Histone deacetylases; Nitric oxide; Suberoylanilide hydroxamic acid; Vorinostat

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aorta / Sulfonamidas / Vasodilatação / Vasodilatadores / Doadores de Óxido Nítrico / Vorinostat / Guanilato Ciclase / Ácidos Hidroxâmicos Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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