Intraductal papillary neoplasms of the bile duct consist of two distinct types specifically associated with clinicopathological features and molecular phenotypes.

Aoki, Yasutaka; Mizuma, Masamichi; Hata, Tatsuo; Aoki, Takeshi; Omori, Yuko; Ono, Yusuke; Mizukami, Yusuke; Unno, Michiaki; Furukawa, Toru

Aoki, Yasutaka; Mizuma, Masamichi; Hata, Tatsuo; Aoki, Takeshi; Omori, Yuko; Ono, Yusuke; Mizukami, Yusuke; Unno, Michiaki; Furukawa, Toru.

Afiliação

Aoki Y; Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan.
Mizuma M; Department of Investigative Pathology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Hata T; Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan.
Aoki T; Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan.
Omori Y; Department of Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan.
Ono Y; Department of Investigative Pathology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Mizukami Y; Institute of Biomedical Research, Sapporo Higashi Tokushukai Hospital, Sapporo, Japan.
Unno M; Institute of Biomedical Research, Sapporo Higashi Tokushukai Hospital, Sapporo, Japan.
Furukawa T; Department of Medicine, Asahikawa Medical University, Asahikawa, Japan.

J Pathol ; 251(1): 38-48, 2020 05.

Article em En | MEDLINE | ID: mdl-32100878

Assuntos

Neoplasias dos Ductos Biliares/patologia; Ductos Biliares/patologia; Carcinoma Papilar/patologia; Fenótipo; Idoso; Neoplasias dos Ductos Biliares/genética; Neoplasias dos Ductos Biliares/metabolismo; Ductos Biliares/metabolismo; Ductos Biliares Intra-Hepáticos/metabolismo; Ductos Biliares Intra-Hepáticos/patologia; Carcinoma Papilar/genética; Feminino; Humanos; Masculino; Pessoa de Meia-Idade; Mutação/genética; Proteínas Proto-Oncogênicas c-ets/genética; Fatores de Transcrição/genética

Palavras-chave

biliary cancer; cholangiocarcinoma; genetics; molecular subtyping; prognosis; targeted sequencing

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenótipo / Neoplasias dos Ductos Biliares / Ductos Biliares / Carcinoma Papilar Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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