Your browser doesn't support javascript.
loading
A mitochondria-targeted fluorescent probe for the detection of endogenous SO2 derivatives in living cells.
Yan, Ye-Hao; Wu, Qiu-Rong; Che, Qiao-Ling; Ding, Man-Man; Xu, Min; Miao, Jun-Ying; Zhao, Bao-Xiang; Lin, Zhao-Min.
Afiliação
  • Yan YH; Institute of Organic Chemistry, School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, P.R. China. bxzhao@sdu.edu.cn.
  • Wu QR; School of Life Science, Shandong University, Qingdao 266237, P.R. China.
  • Che QL; Institute of Organic Chemistry, School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, P.R. China. bxzhao@sdu.edu.cn.
  • Ding MM; Institute of Organic Chemistry, School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, P.R. China. bxzhao@sdu.edu.cn.
  • Xu M; Institute of Organic Chemistry, School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, P.R. China. bxzhao@sdu.edu.cn.
  • Miao JY; School of Life Science, Shandong University, Qingdao 266237, P.R. China.
  • Zhao BX; Institute of Organic Chemistry, School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, P.R. China. bxzhao@sdu.edu.cn.
  • Lin ZM; Institute of Medical Science, the Second Hospital of Shandong University, Jinan 250033, P.R. China. linzhaomin@sdu.edu.cn.
Analyst ; 145(8): 2937-2944, 2020 Apr 14.
Article em En | MEDLINE | ID: mdl-32104823
ABSTRACT
A unique fluorescent probe (ZACA) for the monitoring of SO2 derivatives was developed from coumarin and benzoindoles based on FRET and ICT. ZACA exhibited an active emission signal, large Stokes shift, wide emission window distance, and high photostability. It also possessed many advantages in the ratiometric detection of HSO3-/SO32- including low detection limit and high selectivity and sensitivity. Importantly, ZACA was successfully applied in the ratiometric detection of endogenous HSO3-/SO32- in living cells with excellent cellular imaging capability (1 µM) and mitochondria-targeting ability (co-localization coefficient 0.91).
Assuntos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sulfitos / Corantes Fluorescentes / Mitocôndrias Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sulfitos / Corantes Fluorescentes / Mitocôndrias Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article