In vitro survival of scabies mites.
Clin Exp Dermatol
; 45(6): 712-715, 2020 Aug.
Article
em En
| MEDLINE
| ID: mdl-32112428
ABSTRACT
BACKGROUND:
The correct treatment and management of scabies is expensive and time-consuming, and may have a negative impact on patients and their families.AIM:
To investigate the effects of permethrin 5% cream on scabies mites, and explore mite survival times outside the human body.METHODS:
We performed a nonrandomized controlled study. In total, 20 petri dishes were coated with permethrin 5% cream (treatment group) and 20 plain petri dishes (control group) each had one scabies mite placed in them, and were then observed at baseline and 3, 4, 5, 6, 7, 8 and 12 h from baseline. In the second part of our study, 30 scabies mites from infested patients were investigated in an observational experiment in 30 plain petri dishes at days 0, 3 and 4.RESULTS:
Our data showed that 65% of scabies mites survived after 8 h in the treatment group compared with 75% of mites in the control group. After 12 h, 25% of mites in the treatment group and 60% in the control group were still alive. Data from the observational survival study showed that one mite was alive on day 3, but all mites were dead by day 4.CONCLUSIONS:
This study showed no significant effects of mite survival times with 5% topical permethrin after 8 h, while its efficacy was stronger and significant after 12 h. We recommend the isolation of all mite-infested items for at least 4 days.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Sarcoptes scabiei
/
Permetrina
/
Inseticidas
Tipo de estudo:
Clinical_trials
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article