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Reduced O-GlcNAcylation and tubular hypoxia contribute to the antifibrotic effect of SGLT2 inhibitor dapagliflozin in the diabetic kidney.
Hodrea, Judit; Balogh, Dora B; Hosszu, Adam; Lenart, Lilla; Besztercei, Balazs; Koszegi, Sandor; Sparding, Nadja; Genovese, Federica; Wagner, Laszlo J; Szabo, Attila J; Fekete, Andrea.
Afiliação
  • Hodrea J; MTA-SE "Lendület" Diabetes Research Group, Hungarian Academy of Sciences, Budapest, Hungary.
  • Balogh DB; 1st Department of Pediatrics, Semmelweis University, Budapest, Hungary.
  • Hosszu A; MTA-SE "Lendület" Diabetes Research Group, Hungarian Academy of Sciences, Budapest, Hungary.
  • Lenart L; 1st Department of Pediatrics, Semmelweis University, Budapest, Hungary.
  • Besztercei B; MTA-SE "Lendület" Diabetes Research Group, Hungarian Academy of Sciences, Budapest, Hungary.
  • Koszegi S; 1st Department of Pediatrics, Semmelweis University, Budapest, Hungary.
  • Sparding N; MTA-SE "Lendület" Diabetes Research Group, Hungarian Academy of Sciences, Budapest, Hungary.
  • Genovese F; Institute of Clinical Experimental Research, Semmelweis University, Budapest, Hungary.
  • Wagner LJ; MTA-SE "Lendület" Diabetes Research Group, Hungarian Academy of Sciences, Budapest, Hungary.
  • Szabo AJ; Nordic Bioscience, Biomarkers & Research, Herlev, Denmark.
  • Fekete A; Biomedical Sciences, Faculty of Health and Medical Science, University of Copenhagen, Copenhagen N, Denmark.
Am J Physiol Renal Physiol ; 318(4): F1017-F1029, 2020 04 01.
Article em En | MEDLINE | ID: mdl-32116017
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos Benzidrílicos / Glicosilação / Diabetes Mellitus Experimental / Diabetes Mellitus Tipo 1 / Nefropatias Diabéticas / Inibidores do Transportador 2 de Sódio-Glicose / Glucosídeos / Túbulos Renais Proximais Tipo de estudo: Etiology_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos Benzidrílicos / Glicosilação / Diabetes Mellitus Experimental / Diabetes Mellitus Tipo 1 / Nefropatias Diabéticas / Inibidores do Transportador 2 de Sódio-Glicose / Glucosídeos / Túbulos Renais Proximais Tipo de estudo: Etiology_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article