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Discovery and optimization of 2-aminopyridine derivatives as novel and selective JAK2 inhibitors.
Ma, Xiangyu; Diao, Yanyan; Ge, Huan; Xu, Fangling; Zhu, Lili; Zhao, Zhenjiang; Li, Honglin.
Afiliação
  • Ma X; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science & Technology, Shanghai 200237, China.
  • Diao Y; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science & Technology, Shanghai 200237, China.
  • Ge H; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science & Technology, Shanghai 200237, China.
  • Xu F; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science & Technology, Shanghai 200237, China.
  • Zhu L; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science & Technology, Shanghai 200237, China. Electronic address: zhulfl@ecust.edu.cn.
  • Zhao Z; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science & Technology, Shanghai 200237, China. Electronic address: zhjzhao@ecust.edu.cn.
  • Li H; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science & Technology, Shanghai 200237, China. Electronic address: hlli@ecust.edu.cn.
Bioorg Med Chem Lett ; 30(8): 127048, 2020 04 15.
Article em En | MEDLINE | ID: mdl-32122740

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores de Proteínas Quinases / Janus Quinase 2 / Descoberta de Drogas / Aminopiridinas Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores de Proteínas Quinases / Janus Quinase 2 / Descoberta de Drogas / Aminopiridinas Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article