Human Hepatocyte Nuclear Factor 4-&#945; Encodes Isoforms with Distinct Transcriptional Functions.

Lambert, Élie; Babeu, Jean-Philippe; Simoneau, Joël; Raisch, Jennifer; Lavergne, Laurie; Lévesque, Dominique; Jolibois, Émilie; Avino, Mariano; Scott, Michelle S; Boudreau, François; Boisvert, Francois-Michel

Human Hepatocyte Nuclear Factor 4-α Encodes Isoforms with Distinct Transcriptional Functions.

Lambert, Élie; Babeu, Jean-Philippe; Simoneau, Joël; Raisch, Jennifer; Lavergne, Laurie; Lévesque, Dominique; Jolibois, Émilie; Avino, Mariano; Scott, Michelle S; Boudreau, François; Boisvert, Francois-Michel.

Afiliação

Lambert É; Department of Immunology and Cell Biology, Université de Sherbrooke, Sherbrooke, Québec, J1E 4K8, Canada.
Babeu JP; Department of Immunology and Cell Biology, Université de Sherbrooke, Sherbrooke, Québec, J1E 4K8, Canada.
Simoneau J; Department of Biochemistry and Functional Genomics, Université de Sherbrooke, Sherbrooke, Québec, J1E 4K8, Canada.
Raisch J; Department of Immunology and Cell Biology, Université de Sherbrooke, Sherbrooke, Québec, J1E 4K8, Canada.
Lavergne L; Department of Immunology and Cell Biology, Université de Sherbrooke, Sherbrooke, Québec, J1E 4K8, Canada.
Lévesque D; Department of Immunology and Cell Biology, Université de Sherbrooke, Sherbrooke, Québec, J1E 4K8, Canada.
Jolibois É; Department of Immunology and Cell Biology, Université de Sherbrooke, Sherbrooke, Québec, J1E 4K8, Canada.
Avino M; Department of Biochemistry and Functional Genomics, Université de Sherbrooke, Sherbrooke, Québec, J1E 4K8, Canada.
Scott MS; Department of Biochemistry and Functional Genomics, Université de Sherbrooke, Sherbrooke, Québec, J1E 4K8, Canada.
Boudreau F; Department of Immunology and Cell Biology, Université de Sherbrooke, Sherbrooke, Québec, J1E 4K8, Canada. Electronic address: francois.boudreau@usherbrooke.ca.
Boisvert FM; Department of Immunology and Cell Biology, Université de Sherbrooke, Sherbrooke, Québec, J1E 4K8, Canada. Electronic address: fm.boisvert@usherbrooke.ca.

Mol Cell Proteomics ; 19(5): 808-827, 2020 05.

Article em En | MEDLINE | ID: mdl-32123031

Assuntos

Fator 4 Nuclear de Hepatócito/metabolismo; Transcrição Gênica; Linhagem Celular Tumoral; DNA/metabolismo; Regulação da Expressão Gênica; Redes Reguladoras de Genes; Proteínas de Fluorescência Verde/metabolismo; Fator 4 Nuclear de Hepatócito/genética; Humanos; Ligação Proteica; Isoformas de Proteínas/metabolismo; Receptores Citoplasmáticos e Nucleares/metabolismo; Elementos de Resposta/genética; Fatores de Transcrição/metabolismo; Transcriptoma/genética

Palavras-chave

RNA SEQ; SILAC; Transcriptional regulation; affinity proteomics; bioinformatics; colorectal cancer; nuclear receptors; protein isoforms; quantification; transcription

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transcrição Gênica / Fator 4 Nuclear de Hepatócito Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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