Managing depressive symptoms in people with mild cognitive impairment and mild dementia with a multicomponent psychotherapy intervention: a randomized controlled trial.
Int Psychogeriatr
; 33(3): 217-231, 2021 03.
Article
em En
| MEDLINE
| ID: mdl-32131911
ABSTRACT
OBJECTIVE:
To evaluate the feasibility and effectiveness of the CORDIAL program, a psychosocial intervention consisting of cognitive behavioral therapy (CBT), cognitive rehabilitation, and reminiscence to manage depressive symptoms for people with mild cognitive impairment (MCI) or dementia.DESIGN:
We conducted a randomized controlled trial, based on a two-group (intervention and control), pre-/post-intervention design.SETTING:
Participants were recruited from five different old age psychiatry and memory clinics at outpatients' hospitals.PARTICIPANTS:
Hundred and ninety-eight people with MCI or early-stage dementia were included. INTERVENTION The intervention group (n = 100) received 11 individual weekly sessions of the CORDIAL program. This intervention includes elements from CBT, cognitive rehabilitation, and reminiscence therapy. The control group (n = 98) received treatment-as-usual. MEASUREMENTS We assessed Montgomery-Åsberg Depression Rating Scale (MADRS) (main outcome), Neuropsychiatric Inventory Questionnaire, and Quality of Life in Alzheimer's disease (secondary outcomes) over the course of 4 months and at a 10-month follow-up visit.RESULTS:
A linear mixed model demonstrated that the depressive symptoms assessed by MADRS were significantly more reduced in the intervention groups as compared to the control group (p < 0.001). The effect persisted for 6 months after the intervention. No significant differences between groups were found in neuropsychiatric symptoms or quality of life.CONCLUSION:
Our multicomponent intervention, which comprised 11 individual sessions of CBT, cognitive rehabilitation, and reminiscence therapy, reduced depressive symptoms in people with MCI and dementia.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Psicoterapia
/
Demência
/
Depressão
/
Disfunção Cognitiva
Tipo de estudo:
Clinical_trials
/
Diagnostic_studies
/
Qualitative_research
Limite:
Aged
/
Female
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article