Unprecedented Potential for Neural Drug Discovery Based on Self-Organizing hiPSC Platforms.

Cota-Coronado, Agustín; Durnall, Jennifer C; Díaz, Néstor Fabián; Thompson, Lachlan H; Díaz-Martínez, N Emmanuel

Cota-Coronado, Agustín; Durnall, Jennifer C; Díaz, Néstor Fabián; Thompson, Lachlan H; Díaz-Martínez, N Emmanuel.

Afiliação

Cota-Coronado A; Medical and Pharmaceutical Biotechnology, Center for Research and Assistance in Technology and Design of the State of Jalisco, CIATEJ A.C, 800 Normalistas, Colinas de La Normal, Guadalajara 44270, Jalisco, Mexico.
Durnall JC; The Florey Institute of Neuroscience and Mental Health, 30 Royal Parade, Parkville, VIC 3052, Australia.
Díaz NF; The Florey Institute of Neuroscience and Mental Health, 30 Royal Parade, Parkville, VIC 3052, Australia.
Thompson LH; Departamento de Fisiología y Desarrollo Celular, Instituto Nacional de Perinatología, Mexico City 11000, Mexico.
Díaz-Martínez NE; The Florey Institute of Neuroscience and Mental Health, 30 Royal Parade, Parkville, VIC 3052, Australia.

Molecules ; 25(5)2020 Mar 04.

Article em En | MEDLINE | ID: mdl-32143423

Assuntos

Descoberta de Drogas/métodos; Células-Tronco Pluripotentes Induzidas/citologia; Técnicas de Cultura de Células/métodos; Humanos; Células-Tronco Pluripotentes Induzidas/metabolismo; Organoides/citologia; Organoides/metabolismo

Palavras-chave

3D culture; drug-discovery platforms; hiPSCs; high-throughput screening; self-assembly organoids

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Descoberta de Drogas / Células-Tronco Pluripotentes Induzidas Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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