ITCH as a potential therapeutic target in human cancers.

Yin, Qing; Wyatt, Clayton J; Han, Tao; Smalley, Keiran S M; Wan, Lixin

Yin, Qing; Wyatt, Clayton J; Han, Tao; Smalley, Keiran S M; Wan, Lixin.

Afiliação

Yin Q; Department of Molecular Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
Wyatt CJ; Department of Tumor Biology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
Han T; Department of Molecular Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
Smalley KSM; Department of Tumor Biology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA; Department of Cutaneous Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
Wan L; Department of Molecular Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA; Department of Cutaneous Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA. Electronic address: lixin.wan@moffitt.org.

Semin Cancer Biol ; 67(Pt 2): 117-130, 2020 12.

Article em En | MEDLINE | ID: mdl-32165318

Assuntos

Neoplasias/patologia; Proteínas Repressoras/metabolismo; Ubiquitina-Proteína Ligases/metabolismo; Humanos; Terapia de Alvo Molecular/métodos; Neoplasias/tratamento farmacológico; Neoplasias/metabolismo; Proteínas Repressoras/genética; Microambiente Tumoral/imunologia; Ubiquitina-Proteína Ligases/genética

Palavras-chave

Cancer; Cancer therapy; ITCH; Tumor microenvironment; Ubiquitin E3 ligase

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Ubiquitina-Proteína Ligases / Neoplasias Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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