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Inhibition mechanisms of AcrF9, AcrF8, and AcrF6 against type I-F CRISPR-Cas complex revealed by cryo-EM.
Zhang, Kaiming; Wang, Shuo; Li, Shanshan; Zhu, Yuwei; Pintilie, Grigore D; Mou, Tung-Chung; Schmid, Michael F; Huang, Zhiwei; Chiu, Wah.
Afiliação
  • Zhang K; Department of Bioengineering, James H. Clark Center, Stanford University, Stanford, CA 94305.
  • Wang S; Harbin Institute of Technology (HIT) Center for Life Sciences, School of Life Science and Technology, Harbin Institute of Technology, 150080 Harbin, China.
  • Li S; Department of Bioengineering, James H. Clark Center, Stanford University, Stanford, CA 94305.
  • Zhu Y; Harbin Institute of Technology (HIT) Center for Life Sciences, School of Life Science and Technology, Harbin Institute of Technology, 150080 Harbin, China.
  • Pintilie GD; Department of Bioengineering, James H. Clark Center, Stanford University, Stanford, CA 94305.
  • Mou TC; Center for Biomolecular Structure and Dynamics, University of Montana, Missoula, MT 59812.
  • Schmid MF; CryoEM and Bioimaging Division, Stanford Synchrotron Radiation Lightsource (SSRL), Stanford Linear Accelerator Center (SLAC) National Accelerator Laboratory, Stanford University, Menlo Park, CA 94025.
  • Huang Z; Harbin Institute of Technology (HIT) Center for Life Sciences, School of Life Science and Technology, Harbin Institute of Technology, 150080 Harbin, China; huangzhiwei@hit.edu.cn wahc@stanford.edu.
  • Chiu W; Department of Bioengineering, James H. Clark Center, Stanford University, Stanford, CA 94305; huangzhiwei@hit.edu.cn wahc@stanford.edu.
Proc Natl Acad Sci U S A ; 117(13): 7176-7182, 2020 03 31.
Article em En | MEDLINE | ID: mdl-32170016
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Virais / Interações Hospedeiro-Patógeno / Proteínas Associadas a CRISPR Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Virais / Interações Hospedeiro-Patógeno / Proteínas Associadas a CRISPR Idioma: En Ano de publicação: 2020 Tipo de documento: Article