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Triple artemisinin-based combination therapies versus artemisinin-based combination therapies for uncomplicated Plasmodium falciparum malaria: a multicentre, open-label, randomised clinical trial.
van der Pluijm, Rob W; Tripura, Rupam; Hoglund, Richard M; Pyae Phyo, Aung; Lek, Dysoley; Ul Islam, Akhter; Anvikar, Anupkumar R; Satpathi, Parthasarathi; Satpathi, Sanghamitra; Behera, Prativa Kumari; Tripura, Amar; Baidya, Subrata; Onyamboko, Marie; Chau, Nguyen Hoang; Sovann, Yok; Suon, Seila; Sreng, Sokunthea; Mao, Sivanna; Oun, Savuth; Yen, Sovannary; Amaratunga, Chanaki; Chutasmit, Kitipumi; Saelow, Chalermpon; Runcharern, Ratchadaporn; Kaewmok, Weerayuth; Hoa, Nhu Thi; Thanh, Ngo Viet; Hanboonkunupakarn, Borimas; Callery, James J; Mohanty, Akshaya Kumar; Heaton, James; Thant, Myo; Gantait, Kripasindhu; Ghosh, Tarapada; Amato, Roberto; Pearson, Richard D; Jacob, Christopher G; Gonçalves, Sónia; Mukaka, Mavuto; Waithira, Naomi; Woodrow, Charles J; Grobusch, Martin P; van Vugt, Michele; Fairhurst, Rick M; Cheah, Phaik Yeong; Peto, Thomas J; von Seidlein, Lorenz; Dhorda, Mehul; Maude, Richard J; Winterberg, Markus.
Afiliação
  • van der Pluijm RW; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, UK; Center of Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Academic Medical
  • Tripura R; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, UK.
  • Hoglund RM; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, UK.
  • Pyae Phyo A; Myanmar-Oxford Clinical Research Unit, Yangon, Myanmar.
  • Lek D; National Centre for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia; School of Public Health, National Institute of Public Health, Phnom Penh, Cambodia.
  • Ul Islam A; Ramu Upazila Health Complex, Cox's Bazar, Bangladesh.
  • Anvikar AR; National Institute of Malaria Research, Indian Council of Medical Research, New Delhi, India.
  • Satpathi P; Midnapore Medical College, Midnapur, India.
  • Satpathi S; Ispat General Hospital, Rourkela, India.
  • Behera PK; Ispat General Hospital, Rourkela, India.
  • Tripura A; Agartala Medical College, Tripura, India.
  • Baidya S; Agartala Medical College, Tripura, India.
  • Onyamboko M; Kinshasa Mahidol Oxford Research Unit (KIMORU), Kinshasa, Democratic Republic of the Congo; Kinshasa School of Public Health, Kinshasa, Democratic Republic of the Congo.
  • Chau NH; Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam.
  • Sovann Y; Pailin Provincial Health Department, Pailin, Cambodia.
  • Suon S; National Centre for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia.
  • Sreng S; National Centre for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia.
  • Mao S; Sampov Meas Referral Hospital, Pursat, Cambodia.
  • Oun S; Ratanakiri Referral Hospital, Ratanakiri, Cambodia.
  • Yen S; Ratanakiri Referral Hospital, Ratanakiri, Cambodia.
  • Amaratunga C; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, UK; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, Nat
  • Chutasmit K; Phu Sing hospital, Phu Sing, Sisaket, Thailand.
  • Saelow C; Phu Sing hospital, Phu Sing, Sisaket, Thailand.
  • Runcharern R; Khun Han Hospital, Khun Han, Sisaket, Thailand.
  • Kaewmok W; Khun Han Hospital, Khun Han, Sisaket, Thailand.
  • Hoa NT; Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam.
  • Thanh NV; Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam.
  • Hanboonkunupakarn B; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
  • Callery JJ; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
  • Mohanty AK; Infectious Disease Biology Unit, IGH, Rourkela Research Unit of ILS, Bhubeneswar, DBT, Rourkela, India.
  • Heaton J; Myanmar-Oxford Clinical Research Unit, Yangon, Myanmar.
  • Thant M; Defence Services Medical Research Centre, Yangon, Myanmar.
  • Gantait K; Midnapore Medical College, Midnapur, India.
  • Ghosh T; Midnapore Medical College, Midnapur, India.
  • Amato R; Nuffield Department of Medicine and MRC Centre for Genomics and Global Health, Big Data Institute, University of Oxford, Oxford, UK; Wellcome Sanger Institute, Hinxton, UK.
  • Pearson RD; Nuffield Department of Medicine and MRC Centre for Genomics and Global Health, Big Data Institute, University of Oxford, Oxford, UK; Wellcome Sanger Institute, Hinxton, UK.
  • Jacob CG; Wellcome Sanger Institute, Hinxton, UK.
  • Gonçalves S; Wellcome Sanger Institute, Hinxton, UK.
  • Mukaka M; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, UK.
  • Waithira N; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, UK.
  • Woodrow CJ; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, UK.
  • Grobusch MP; Center of Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands.
  • van Vugt M; Center of Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands.
  • Fairhurst RM; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, USA; AstraZeneca, Gaithersburg, MD, USA.
  • Cheah PY; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, UK.
  • Peto TJ; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, UK.
  • von Seidlein L; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, UK.
  • Dhorda M; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, UK; WorldWide Antimalarial Resistance Network - Asia Regional Centre, Bangkok, Thailand.
  • Maude RJ; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, UK; The Open University, Milton Keynes, UK; Harvard T H Chan School of Public Health, Harvard University,
  • Winterberg M; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, UK.
Lancet ; 395(10233): 1345-1360, 2020 04 25.
Article em En | MEDLINE | ID: mdl-32171078
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Malária Falciparum / Artemisininas / Antimaláricos Tipo de estudo: Clinical_trials Limite: Adolescent / Adult / Female / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Malária Falciparum / Artemisininas / Antimaláricos Tipo de estudo: Clinical_trials Limite: Adolescent / Adult / Female / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article