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Lack of an association between carcinoma of the stomach and the major histocompatibility complex (HLA) in Cape Coloureds.
Martell, R W; van Eeden, P J; Madden, M V; du Toit, E D; Dent, D M.
Afiliação
  • Martell RW; Provincial Laboratory for Tissue Immunology, Observatory, Cape Town, South Africa.
Tissue Antigens ; 32(3): 150-4, 1988 Sep.
Article em En | MEDLINE | ID: mdl-3217931
A possible genetic contribution to the high incidence of gastric carcinoma in the Cape Coloured population of the Western Cape region of South Africa was investigated. The HLA-A, B, C, DR and DQ antigens were determined with a microcytotoxicity assay, and their frequencies compared in 124 individuals with gastric carcinoma and 4,560 controls. No significant difference was found, thus supporting the view that a genetic component has a minor, if any, role in gastric carcinogenesis.
Assuntos
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Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / População Negra / Complexo Principal de Histocompatibilidade Tipo de estudo: Risk_factors_studies Limite: Humans País como assunto: Africa Idioma: En Ano de publicação: 1988 Tipo de documento: Article
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Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / População Negra / Complexo Principal de Histocompatibilidade Tipo de estudo: Risk_factors_studies Limite: Humans País como assunto: Africa Idioma: En Ano de publicação: 1988 Tipo de documento: Article