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EML4-ALK V3 oncogenic fusion proteins promote microtubule stabilization and accelerated migration through NEK9 and NEK7.
O'Regan, Laura; Barone, Giancarlo; Adib, Rozita; Woo, Chang Gok; Jeong, Hui Jeong; Richardson, Emily L; Richards, Mark W; Muller, Patricia A J; Collis, Spencer J; Fennell, Dean A; Choi, Jene; Bayliss, Richard; Fry, Andrew M.
Afiliação
  • O'Regan L; Department of Molecular and Cell Biology, University of Leicester, Lancaster Road, Leicester LE1 9HN, UK lo29@le.ac.uk amf5@le.ac.uk.
  • Barone G; Department of Molecular and Cell Biology, University of Leicester, Lancaster Road, Leicester LE1 9HN, UK.
  • Adib R; Department of Oncology and Metabolism, Sheffield Institute for Nucleic Acids (SInFoNiA), University of Sheffield, Beech Hill Road, Sheffield S10 2RX, UK.
  • Woo CG; Department of Molecular and Cell Biology, University of Leicester, Lancaster Road, Leicester LE1 9HN, UK.
  • Jeong HJ; Department of Pathology, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju 28644, Korea.
  • Richardson EL; Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
  • Richards MW; Department of Molecular and Cell Biology, University of Leicester, Lancaster Road, Leicester LE1 9HN, UK.
  • Muller PAJ; School of Molecular and Cellular Biology, Astbury Centre for Structural Molecular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK.
  • Collis SJ; Cancer Research UK Manchester Institute, University of Manchester, Alderley Park SK10 4TG, UK.
  • Fennell DA; Department of Oncology and Metabolism, Sheffield Institute for Nucleic Acids (SInFoNiA), University of Sheffield, Beech Hill Road, Sheffield S10 2RX, UK.
  • Choi J; Cancer Research Centre, University of Leicester, Robert Kilpatrick Clinical Sciences Building, Leicester LE1 9HN, UK.
  • Bayliss R; Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
  • Fry AM; School of Molecular and Cellular Biology, Astbury Centre for Structural Molecular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK.
J Cell Sci ; 133(9)2020 05 11.
Article em En | MEDLINE | ID: mdl-32184261

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article