Spiro-oxindole Piperidines and 3-(Azetidin-3-yl)-1<i>H</i>-benzimidazol-2-ones as mGlu<sub>2</sub> Receptor PAMs.

Spiro-oxindole Piperidines and 3-(Azetidin-3-yl)-1H-benzimidazol-2-ones as mGlu₂ Receptor PAMs.

de Lucas, Ana Isabel; Vega, Juan Antonio; Matesanz, Encarnación; Linares, María Lourdes; García Molina, Aránzazu; Tresadern, Gary; Lavreysen, Hilde; Trabanco, Andrés A; Cid, José María.

Afiliação

de Lucas AI; Discovery Chemistry, Janssen Research & Development, Division of Janssen-Cilag S.A., Jarama 75A, Toledo 45007, Spain.
Vega JA; Discovery Chemistry, Janssen Research & Development, Division of Janssen-Cilag S.A., Jarama 75A, Toledo 45007, Spain.
Matesanz E; Discovery Chemistry, Janssen Research & Development, Division of Janssen-Cilag S.A., Jarama 75A, Toledo 45007, Spain.
Linares ML; Discovery Chemistry, Janssen Research & Development, Division of Janssen-Cilag S.A., Jarama 75A, Toledo 45007, Spain.
García Molina A; Discovery Chemistry, Janssen Research & Development, Division of Janssen-Cilag S.A., Jarama 75A, Toledo 45007, Spain.
Tresadern G; Computational Chemistry, Discovery Neuroscience, Janssen Research & Development, Division of Janssen Pharmaceutica NV, Turnhoutseweg 30, B-2340 Beerse, Belgium.
Lavreysen H; Discovery Neuroscience, Janssen Research & Development, Division of Janssen Pharmaceutica NV, Turnhoutseweg 30, B-2340 Beerse, Belgium.
Trabanco AA; Discovery Chemistry, Janssen Research & Development, Division of Janssen-Cilag S.A., Jarama 75A, Toledo 45007, Spain.
Cid JM; Discovery Chemistry, Janssen Research & Development, Division of Janssen-Cilag S.A., Jarama 75A, Toledo 45007, Spain.

ACS Med Chem Lett ; 11(3): 303-308, 2020 Mar 12.

Article em En | MEDLINE | ID: mdl-32184961

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article