Prevalence of multidrug-resistant organisms on palliative care patients in a university hospital-bound palliative care unit: A prospective cohort analysis.
Palliat Med
; 34(6): 776-783, 2020 06.
Article
em En
| MEDLINE
| ID: mdl-32186249
ABSTRACT
BACKGROUND:
Multidrug-resistant organisms are a growing challenge and burden to patient care. To date, there are only data concerning the prevalence of methicillin-resistant Staphylococcus aureus infections. Thus, numbers of other multidrug-resistant organisms can only be extrapolated and inferred from more or less comparable cohorts.AIM:
To evaluate the prevalence of multidrug-resistant organisms on palliative care in-patients.DESIGN:
A prospective cohort analysis. SETTING/PARTICIPANTS:
A University Hospital-bound palliative care unit, in which all patients admitted to the unit were screened for inclusion.RESULTS:
In total, 304 patients were included in this study. The prevalence for methicillin-resistant Staphylococcus aureus of 5.2% (95% confidence interval 2.9%-8.4%), for vancomycin-resistant Enterococcus faecium of 10.5% (95% confidence interval 7.2%-14.8%), for Ciprofloxacin-resistant-extended spectrum beta-lactamases isolates of 5.8% (95% confidence interval 3.4%-9.3%) and Ciprofloxacin-resistant Carbapenem-resistant Gram-negative bacteria of 0.3% (95% confidence interval 0%-1.3%) was calculated. Except for methicillin-resistant Staphylococcus aureus, patients carrying a multidrug-resistant organism had a significant longer duration of hospitalization. Median length of stay was 12 days (interquartile range 14.5, no multidrug-resistant organisms), 14.5 days (interquartile range 15, methicillin-resistant Staphylococcus aureus), 21 days (interquartile range 16.5, vancomycin-resistant enterococci), 22 days (interquartile range 20.75, Ciprofloxacin-resistant-extended spectrum beta-lactamases) and 32 days (interquartile range 22.00) for patients carrying two organisms.CONCLUSION:
There is a high prevalence of all multidrug-resistant organisms within the hospitalized palliative care patients. However, the multidrug-resistant organisms do not seem to impact the survival within this cohort. Further studies should evaluate additional end-points, for example, quality of life, which are of special interest in this cohort.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Cuidados Paliativos
/
Bactérias
/
Farmacorresistência Bacteriana
/
Hospitais
Tipo de estudo:
Etiology_studies
/
Incidence_studies
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Observational_studies
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Prevalence_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article