Injectable calcium phosphate ceramics prevent osteoclastic differentiation and osteoporotic bone loss: Potential applications for regional osteolysis.

Heng, Shujun; Lu, Zhenhui; Liu, Qian; Jiang, Tongmeng; He, Mingwei; Song, Fangming; Zhao, Jinmin; Zheng, Li

Heng, Shujun; Lu, Zhenhui; Liu, Qian; Jiang, Tongmeng; He, Mingwei; Song, Fangming; Zhao, Jinmin; Zheng, Li.

Afiliação

Heng S; Guangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
Lu Z; Guangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
Liu Q; Guangxi Key Laboratory of Regenerative Medicine & International Joint Laboratory on Regeneration of Bone and Soft Tissue, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
Jiang T; Guangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
He M; Guangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
Song F; Guangxi Key Laboratory of Regenerative Medicine & International Joint Laboratory on Regeneration of Bone and Soft Tissue, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China. Electronic address: fangmingsong109@163.com.
Zhao J; Guangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China; Guangxi Key Laboratory of Regenerative Medicine & International Joint Laboratory on Regeneration of Bone and Soft Tissue, The
Zheng L; Guangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China. Electronic address: zhengli224@163.com.

Mater Sci Eng C Mater Biol Appl ; 110: 110691, 2020 May.

Article em En | MEDLINE | ID: mdl-32204116

Assuntos

Doenças Ósseas Metabólicas/tratamento farmacológico; Fosfatos de Cálcio/farmacologia; Diferenciação Celular/efeitos dos fármacos; Cerâmica/farmacologia; Osteoclastos/efeitos dos fármacos; Osteólise/tratamento farmacológico; Osteoporose/tratamento farmacológico; Animais; Doenças Ósseas Metabólicas/metabolismo; Células da Medula Óssea/efeitos dos fármacos; Células da Medula Óssea/metabolismo; Reabsorção Óssea/tratamento farmacológico; Reabsorção Óssea/metabolismo; Linhagem Celular; Injeções/métodos; Macrófagos/efeitos dos fármacos; Macrófagos/metabolismo; Camundongos; Camundongos Endogâmicos C57BL; NF-kappa B/metabolismo; Fatores de Transcrição NFATC/metabolismo; Osteoclastos/metabolismo; Osteogênese/efeitos dos fármacos; Osteólise/metabolismo; Osteoporose/metabolismo; Células RAW 264.7

Palavras-chave

Bone regeneration; Calcium phosphates powders; Osteoclast; Osteoinduction; Osteolysis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteoclastos / Osteólise / Osteoporose / Doenças Ósseas Metabólicas / Fosfatos de Cálcio / Diferenciação Celular / Cerâmica Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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