CD20 is dispensable for B-cell receptor signaling but is required for proper actin polymerization, adhesion and migration of malignant B cells.

Kozlova, Veronika; Ledererova, Aneta; Ladungova, Adriana; Peschelova, Helena; Janovska, Pavlina; Slusarczyk, Aleksander; Domagala, Joanna; Kopcil, Pavel; Vakulova, Viera; Oppelt, Jan; Bryja, Vitezslav; Doubek, Michael; Mayer, Jiri; Pospisilova, Sarka; Smida, Michal

Kozlova, Veronika; Ledererova, Aneta; Ladungova, Adriana; Peschelova, Helena; Janovska, Pavlina; Slusarczyk, Aleksander; Domagala, Joanna; Kopcil, Pavel; Vakulova, Viera; Oppelt, Jan; Bryja, Vitezslav; Doubek, Michael; Mayer, Jiri; Pospisilova, Sarka; Smida, Michal.

Afiliação

Kozlova V; Central European Institute of Technology (CEITEC), Masaryk University, Brno, Czech Republic.
Ledererova A; Department of Internal Medicine - Hematology and Oncology, Medical Faculty of Masaryk University and University Hospital Brno, Brno, Czech Republic.
Ladungova A; Central European Institute of Technology (CEITEC), Masaryk University, Brno, Czech Republic.
Peschelova H; Department of Internal Medicine - Hematology and Oncology, Medical Faculty of Masaryk University and University Hospital Brno, Brno, Czech Republic.
Janovska P; Central European Institute of Technology (CEITEC), Masaryk University, Brno, Czech Republic.
Slusarczyk A; Central European Institute of Technology (CEITEC), Masaryk University, Brno, Czech Republic.
Domagala J; Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic.
Kopcil P; Department of Immunology, Medical University of Warsaw, Warsaw, Poland.
Vakulova V; Department of Immunology, Medical University of Warsaw, Warsaw, Poland.
Oppelt J; Central European Institute of Technology (CEITEC), Masaryk University, Brno, Czech Republic.
Bryja V; Central European Institute of Technology (CEITEC), Masaryk University, Brno, Czech Republic.
Doubek M; Central European Institute of Technology (CEITEC), Masaryk University, Brno, Czech Republic.
Mayer J; Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic.
Pospisilova S; Central European Institute of Technology (CEITEC), Masaryk University, Brno, Czech Republic.
Smida M; Department of Internal Medicine - Hematology and Oncology, Medical Faculty of Masaryk University and University Hospital Brno, Brno, Czech Republic.

PLoS One ; 15(3): e0229170, 2020.

Article em En | MEDLINE | ID: mdl-32210425

Assuntos

Actinas/metabolismo; Antígenos CD20/fisiologia; Linfócitos B/fisiologia; Leucemia de Células B/patologia; Linfoma de Células B/patologia; Receptores de Antígenos de Linfócitos B/metabolismo; Animais; Antígenos CD20/genética; Antígenos CD20/metabolismo; Linfócitos B/patologia; Adesão Celular/fisiologia; Linhagem Celular Tumoral; Movimento Celular/fisiologia; Técnicas de Silenciamento de Genes; Humanos; Leucemia de Células B/metabolismo; Linfoma de Células B/metabolismo; Camundongos; Camundongos Endogâmicos NOD; Camundongos SCID; Camundongos Transgênicos; Polimerização; Multimerização Proteica/fisiologia; Transdução de Sinais/imunologia

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos B / Receptores de Antígenos de Linfócitos B / Leucemia de Células B / Linfoma de Células B / Actinas / Antígenos CD20 Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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